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Sensitivity of different DNA extraction methods and PCR to detect resistance in patients with leprosy stratified by the bacilloscopic index
INTRODUCTION: Antimicrobial resistance in leprosy is an emerging problem, and the quantitative impact of low bacilloscopic indexes (BIs) on the sensitivity of molecular tests is unknown. We aimed to evaluate the sensitivity of gene sequencing for the detection of mutations related to antimicrobial r...
Autores principales: | Sevilha-Santos, Lais, Aquino, Danielle Costa, Hans Neto, Günter, Costa, Fabiano José Queiroz, de Sousa, Carlos Augusto Felipe, Morelo, Elaine Faria, Santos Júnior, Agenor de Castro Moreira dos, Gomes, Ciro Martins |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459058/ https://www.ncbi.nlm.nih.gov/pubmed/35772498 http://dx.doi.org/10.1016/j.bjid.2022.102381 |
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