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Long term high glucose exposure induces premature senescence in retinal endothelial cells

Purpose: Features of cellular senescence have been described in diabetic retinal vasculature. The aim of this study was to investigate how the high glucose microenvironment impacts on the senescence program of retinal endothelial cells. Methods: Human retinal microvascular endothelial cells were cul...

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Detalles Bibliográficos
Autores principales:	Bertelli, Pietro Maria, Pedrini, Edoardo, Hughes, David, McDonnell, Shannon, Pathak, Varun, Peixoto, Elisa, Guduric-Fuchs, Jasenka, Stitt, Alan W, Medina, Reinhold J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459081/ https://www.ncbi.nlm.nih.gov/pubmed/36091370 http://dx.doi.org/10.3389/fphys.2022.929118

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