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Loss of MHC-I antigen presentation correlated with immune checkpoint blockade tolerance in MAPK inhibitor-resistant melanoma
Immune checkpoint blockade and MAPK-targeted combined therapy is a promising regimen for advanced melanoma patients. However, the clinical benefit from this combo regimen remains limited, especially in patients who acquired resistance to MAPK-targeted therapy. Here, we systematically characterized t...
Autores principales: | Yu, Jing, Wu, Xi, Song, Jinen, Zhao, Yujie, Li, Huifang, Luo, Min, Liu, Xiaowei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459091/ https://www.ncbi.nlm.nih.gov/pubmed/36091815 http://dx.doi.org/10.3389/fphar.2022.928226 |
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