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Structural and functional analysis of the small GTPase ARF1 reveals a pivotal role of its GTP-binding domain in controlling of the generation of viral inclusion bodies and replication of grass carp reovirus

Grass carp reovirus (GCRV) is the most pathogenic double-stranded (ds) RNA virus among the isolated aquareoviruses. The molecular mechanisms by which GCRV utilizes host factors to generate its infectious compartments beneficial for viral replication and infection are poorly understood. Here, we disc...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Li, Pengwei, Lu, Riye, Ouyang, Songying, Chang, Ming Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459132/
https://www.ncbi.nlm.nih.gov/pubmed/36091067
http://dx.doi.org/10.3389/fimmu.2022.956587