Cargando…

Gut microbiota: Linking nutrition and perinatal depression

Perinatal depression is a mood disorder that is reported in women during pregnancy (prenatal) and after childbirth (postnatal). The onset of perinatal depression is associated with changes in reproductive hormones, stress hormones and neurosteroids. These chemical compounds can be modulated by the g...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Jia, Zhou, Bi, Kan, Juntao, Liu, Guangya, Zhang, Sheng, Si, Liang, Zhang, Xianping, Yang, Xue, Ma, Junhua, Cheng, Junrui, Liu, Xiaobo, Yang, Yongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459161/
https://www.ncbi.nlm.nih.gov/pubmed/36093196
http://dx.doi.org/10.3389/fcimb.2022.932309
_version_ 1784786444813860864
author Song, Jia
Zhou, Bi
Kan, Juntao
Liu, Guangya
Zhang, Sheng
Si, Liang
Zhang, Xianping
Yang, Xue
Ma, Junhua
Cheng, Junrui
Liu, Xiaobo
Yang, Yongde
author_facet Song, Jia
Zhou, Bi
Kan, Juntao
Liu, Guangya
Zhang, Sheng
Si, Liang
Zhang, Xianping
Yang, Xue
Ma, Junhua
Cheng, Junrui
Liu, Xiaobo
Yang, Yongde
author_sort Song, Jia
collection PubMed
description Perinatal depression is a mood disorder that is reported in women during pregnancy (prenatal) and after childbirth (postnatal). The onset of perinatal depression is associated with changes in reproductive hormones, stress hormones and neurosteroids. These chemical compounds can be modulated by the gut microbiota, which may affect maternal mental health during the perinatal period via the gut-brain-axis. Recent studies suggest that nutritional and dietary interventions (vitamin D, ω-3 fatty acids, iron, and fiber) effectively prevent or mitigate maternal depression and anxiety, but their efficacy is confounded by various factors, including the gut microbiota. Probiotics are efficacious in maintaining microbiota homeostasis, and thus, have the potential to modulate the development of perinatal mood disorders, despite no evidence in human. Therefore, clinical trials are warranted to investigate the role of probiotic supplementation in perinatal depression and behavioral changes. This article reviews the interplay between nutrition, gut microbiota and mood and cognition, and the evidence suggesting that probiotics affect the onset and development of perinatal depression.
format Online
Article
Text
id pubmed-9459161
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-94591612022-09-10 Gut microbiota: Linking nutrition and perinatal depression Song, Jia Zhou, Bi Kan, Juntao Liu, Guangya Zhang, Sheng Si, Liang Zhang, Xianping Yang, Xue Ma, Junhua Cheng, Junrui Liu, Xiaobo Yang, Yongde Front Cell Infect Microbiol Cellular and Infection Microbiology Perinatal depression is a mood disorder that is reported in women during pregnancy (prenatal) and after childbirth (postnatal). The onset of perinatal depression is associated with changes in reproductive hormones, stress hormones and neurosteroids. These chemical compounds can be modulated by the gut microbiota, which may affect maternal mental health during the perinatal period via the gut-brain-axis. Recent studies suggest that nutritional and dietary interventions (vitamin D, ω-3 fatty acids, iron, and fiber) effectively prevent or mitigate maternal depression and anxiety, but their efficacy is confounded by various factors, including the gut microbiota. Probiotics are efficacious in maintaining microbiota homeostasis, and thus, have the potential to modulate the development of perinatal mood disorders, despite no evidence in human. Therefore, clinical trials are warranted to investigate the role of probiotic supplementation in perinatal depression and behavioral changes. This article reviews the interplay between nutrition, gut microbiota and mood and cognition, and the evidence suggesting that probiotics affect the onset and development of perinatal depression. Frontiers Media S.A. 2022-08-26 /pmc/articles/PMC9459161/ /pubmed/36093196 http://dx.doi.org/10.3389/fcimb.2022.932309 Text en Copyright © 2022 Song, Zhou, Kan, Liu, Zhang, Si, Zhang, Yang, Ma, Cheng, Liu and Yang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Song, Jia
Zhou, Bi
Kan, Juntao
Liu, Guangya
Zhang, Sheng
Si, Liang
Zhang, Xianping
Yang, Xue
Ma, Junhua
Cheng, Junrui
Liu, Xiaobo
Yang, Yongde
Gut microbiota: Linking nutrition and perinatal depression
title Gut microbiota: Linking nutrition and perinatal depression
title_full Gut microbiota: Linking nutrition and perinatal depression
title_fullStr Gut microbiota: Linking nutrition and perinatal depression
title_full_unstemmed Gut microbiota: Linking nutrition and perinatal depression
title_short Gut microbiota: Linking nutrition and perinatal depression
title_sort gut microbiota: linking nutrition and perinatal depression
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459161/
https://www.ncbi.nlm.nih.gov/pubmed/36093196
http://dx.doi.org/10.3389/fcimb.2022.932309
work_keys_str_mv AT songjia gutmicrobiotalinkingnutritionandperinataldepression
AT zhoubi gutmicrobiotalinkingnutritionandperinataldepression
AT kanjuntao gutmicrobiotalinkingnutritionandperinataldepression
AT liuguangya gutmicrobiotalinkingnutritionandperinataldepression
AT zhangsheng gutmicrobiotalinkingnutritionandperinataldepression
AT siliang gutmicrobiotalinkingnutritionandperinataldepression
AT zhangxianping gutmicrobiotalinkingnutritionandperinataldepression
AT yangxue gutmicrobiotalinkingnutritionandperinataldepression
AT majunhua gutmicrobiotalinkingnutritionandperinataldepression
AT chengjunrui gutmicrobiotalinkingnutritionandperinataldepression
AT liuxiaobo gutmicrobiotalinkingnutritionandperinataldepression
AT yangyongde gutmicrobiotalinkingnutritionandperinataldepression