Proteogenomic analysis in an early onset diffuse gastric cancer patient revealed alterations in PIK3R1, TP53, SMAD4 and a potential role of the PI3K-AKT and EGFR pathways: a case report

BACKGROUND: Early-onset gastric cancers (EOGC) are poor prognosis hard-to treat malignancies that affect young individuals (<45 years old). CASE DESCRIPTION: Herein we describe the case of a 26-year-old female EOGC patient that initially displayed stable disease after first-line CAPOX plus immuno...

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Detalles Bibliográficos
Autores principales: Cordova-Delgado, Miguel, Pinto, Mauricio P., Pizarro, Gonzalo, Koch, Elard, Vargas, Cristian, Hernández, Mauricio, Nourdin, Guillermo, Saldivia, Pablo, Rodriguez Z., Maria Paz, Berkovits, Alejandro, Manque, Patricio, Rios, Juvenal A., Garcia-Bloj, Benjamin, Garrido, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459214/
https://www.ncbi.nlm.nih.gov/pubmed/36092312
http://dx.doi.org/10.21037/jgo-21-780

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