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Altered gene expression due to aberrant DNA methylation correlates with responsiveness to anti‐EGFR antibody treatment

The cetuximab gene expression signature and DNA methylation status of colorectal cancer (CRC) are predictive of the therapeutic effects of anti‐epidermal growth factor receptor (EGFR) antibody therapy. As DNA methylation is a means of regulating gene expression, it may play an important role in the...

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Detalles Bibliográficos
Autores principales:	Otsuki, Yasufumi, Ouchi, Kota, Takahashi, Shin, Sasaki, Keiju, Sakamoto, Yasuhiro, Okita, Akira, Ishioka, Chikashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459254/ https://www.ncbi.nlm.nih.gov/pubmed/35403373 http://dx.doi.org/10.1111/cas.15367

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