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The postpartum uterine ultrasonographic scale in assessment of uterine involution after cesarean section in treated thrombophilia pregnant patients at term

BACKGROUND: Pregnancy is a prothrombotic condition which can be abnormally exaggerated in women with thrombophilia. METHODS: In a prospective study, patients who delivered at term, by cesarean section, between 1 October 2017 and 1 December 2021, who already had a diagnosis of thrombophilia before co...

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Autores principales: Filip, Catalina, Covali, Roxana, Socolov, Demetra, Carauleanu, Alexandru, Tanasa, Ingrid Andrada, Scripcariu, Ioana Sadyie, Ciuhodaru, Madalina, Butureanu, Tudor, Pavaleanu, Ioana, Akad, Mona, Boiculese, Lucian Vasile, Socolov, Razvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459266/
https://www.ncbi.nlm.nih.gov/pubmed/36082463
http://dx.doi.org/10.1002/jcla.24645
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author Filip, Catalina
Covali, Roxana
Socolov, Demetra
Carauleanu, Alexandru
Tanasa, Ingrid Andrada
Scripcariu, Ioana Sadyie
Ciuhodaru, Madalina
Butureanu, Tudor
Pavaleanu, Ioana
Akad, Mona
Boiculese, Lucian Vasile
Socolov, Razvan
author_facet Filip, Catalina
Covali, Roxana
Socolov, Demetra
Carauleanu, Alexandru
Tanasa, Ingrid Andrada
Scripcariu, Ioana Sadyie
Ciuhodaru, Madalina
Butureanu, Tudor
Pavaleanu, Ioana
Akad, Mona
Boiculese, Lucian Vasile
Socolov, Razvan
author_sort Filip, Catalina
collection PubMed
description BACKGROUND: Pregnancy is a prothrombotic condition which can be abnormally exaggerated in women with thrombophilia. METHODS: In a prospective study, patients who delivered at term, by cesarean section, between 1 October 2017 and 1 December 2021, who already had a diagnosis of thrombophilia before coming to our hospital, were included in the study group (n = 80). A similar number of nonthrombophilia patients (n = 80) without any history of thrombotic events, age‐ and para‐matched with the study group, were included in the control group. The postpartum uterine ultrasonographic scale (PUUS) values, in the first 24–48 h, were correlated with the patients' data. RESULTS: The P‐LCR (platelet large cell ratio), was significantly higher in the treated thrombophilia group (p = 0.042). There was no correlation between PUUS and complete blood count values, coagulation factors, maternal characteristics, or fetal outcomes, except for postpartum neutrophils (p = 0.047) and postpartum platelet count (p = 0.046). CONCLUSIONS: Postpartum uterine involution was not significantly different, after cesarean section, between treated thrombophilia patients and nonthrombophilia patients. Involution correlated only with postpartum neutrophils and postpartum platelet count.
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spelling pubmed-94592662022-09-12 The postpartum uterine ultrasonographic scale in assessment of uterine involution after cesarean section in treated thrombophilia pregnant patients at term Filip, Catalina Covali, Roxana Socolov, Demetra Carauleanu, Alexandru Tanasa, Ingrid Andrada Scripcariu, Ioana Sadyie Ciuhodaru, Madalina Butureanu, Tudor Pavaleanu, Ioana Akad, Mona Boiculese, Lucian Vasile Socolov, Razvan J Clin Lab Anal Research Articles BACKGROUND: Pregnancy is a prothrombotic condition which can be abnormally exaggerated in women with thrombophilia. METHODS: In a prospective study, patients who delivered at term, by cesarean section, between 1 October 2017 and 1 December 2021, who already had a diagnosis of thrombophilia before coming to our hospital, were included in the study group (n = 80). A similar number of nonthrombophilia patients (n = 80) without any history of thrombotic events, age‐ and para‐matched with the study group, were included in the control group. The postpartum uterine ultrasonographic scale (PUUS) values, in the first 24–48 h, were correlated with the patients' data. RESULTS: The P‐LCR (platelet large cell ratio), was significantly higher in the treated thrombophilia group (p = 0.042). There was no correlation between PUUS and complete blood count values, coagulation factors, maternal characteristics, or fetal outcomes, except for postpartum neutrophils (p = 0.047) and postpartum platelet count (p = 0.046). CONCLUSIONS: Postpartum uterine involution was not significantly different, after cesarean section, between treated thrombophilia patients and nonthrombophilia patients. Involution correlated only with postpartum neutrophils and postpartum platelet count. John Wiley and Sons Inc. 2022-08-05 /pmc/articles/PMC9459266/ /pubmed/36082463 http://dx.doi.org/10.1002/jcla.24645 Text en © 2022 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
Filip, Catalina
Covali, Roxana
Socolov, Demetra
Carauleanu, Alexandru
Tanasa, Ingrid Andrada
Scripcariu, Ioana Sadyie
Ciuhodaru, Madalina
Butureanu, Tudor
Pavaleanu, Ioana
Akad, Mona
Boiculese, Lucian Vasile
Socolov, Razvan
The postpartum uterine ultrasonographic scale in assessment of uterine involution after cesarean section in treated thrombophilia pregnant patients at term
title The postpartum uterine ultrasonographic scale in assessment of uterine involution after cesarean section in treated thrombophilia pregnant patients at term
title_full The postpartum uterine ultrasonographic scale in assessment of uterine involution after cesarean section in treated thrombophilia pregnant patients at term
title_fullStr The postpartum uterine ultrasonographic scale in assessment of uterine involution after cesarean section in treated thrombophilia pregnant patients at term
title_full_unstemmed The postpartum uterine ultrasonographic scale in assessment of uterine involution after cesarean section in treated thrombophilia pregnant patients at term
title_short The postpartum uterine ultrasonographic scale in assessment of uterine involution after cesarean section in treated thrombophilia pregnant patients at term
title_sort postpartum uterine ultrasonographic scale in assessment of uterine involution after cesarean section in treated thrombophilia pregnant patients at term
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459266/
https://www.ncbi.nlm.nih.gov/pubmed/36082463
http://dx.doi.org/10.1002/jcla.24645
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