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Silybin suppresses ovarian cancer cell proliferation by inhibiting isocitrate dehydrogenase 1 activity

Metabolic reprogramming is a sign of malignant tumors, and targeting the metabolism of tumor cells has become a promising therapeutic approach. Here, we report that Silybin (a nontoxic flavonoid commonly used for liver protection) exhibits prominent anti‐tumor effects on human ovarian cancer cells....

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Detalles Bibliográficos
Autores principales: Wei, Zibo, Ye, Shuangyan, Feng, Haipeng, Zeng, Chong, Dong, Xinhuai, Zeng, Xiaokang, Zeng, Liming, Lin, Xu, Liu, Qiuzhen, Yao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459272/
https://www.ncbi.nlm.nih.gov/pubmed/35730256
http://dx.doi.org/10.1111/cas.15470

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