Cargando…
Silybin suppresses ovarian cancer cell proliferation by inhibiting isocitrate dehydrogenase 1 activity
Metabolic reprogramming is a sign of malignant tumors, and targeting the metabolism of tumor cells has become a promising therapeutic approach. Here, we report that Silybin (a nontoxic flavonoid commonly used for liver protection) exhibits prominent anti‐tumor effects on human ovarian cancer cells....
Autores principales: | Wei, Zibo, Ye, Shuangyan, Feng, Haipeng, Zeng, Chong, Dong, Xinhuai, Zeng, Xiaokang, Zeng, Liming, Lin, Xu, Liu, Qiuzhen, Yao, Jie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459272/ https://www.ncbi.nlm.nih.gov/pubmed/35730256 http://dx.doi.org/10.1111/cas.15470 |
Ejemplares similares
-
SHARPIN promotes cell proliferation of cholangiocarcinoma and inhibits ferroptosis via p53/SLC7A11/GPX4 signaling
por: Zeng, Chong, et al.
Publicado: (2022) -
A High-Salt Diet Disturbs the Development and Function of Natural Killer Cells in Mice
por: Zeng, Xiaokang, et al.
Publicado: (2020) -
Mutation of Isocitrate Dehydrogenase 1 in Cholangiocarcinoma Impairs Tumor Progression by Inhibiting Isocitrate Metabolism
por: Su, Li, et al.
Publicado: (2020) -
Isocitrate dehydrogenase mutations in myeloid malignancies
por: Medeiros, B C, et al.
Publicado: (2017) -
Development of a novel glycolysis-related genes signature for isocitrate dehydrogenase 1-associated glioblastoma multiforme
por: Cai, Xiaomin, et al.
Publicado: (2022)