Approaches to Selecting “Time Zero” in External Control Arms with Multiple Potential Entry Points: A Simulation Study of 8 Approaches

BACKGROUND: When including data from an external control arm to estimate comparative effectiveness, there is a methodological choice of when to set “time zero,” the point at which a patient would be eligible/enrolled in a contemporary study. Where patients receive multiple lines of eligible therapy...

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Detalles Bibliográficos
Autores principales: Hatswell, Anthony J., Deighton, Kevin, Snider, Julia Thornton, Brookhart, M. Alan, Faghmous, Imi, Patel, Anik R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459359/
https://www.ncbi.nlm.nih.gov/pubmed/35514320
http://dx.doi.org/10.1177/0272989X221096070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459359/
https://www.ncbi.nlm.nih.gov/pubmed/35514320
http://dx.doi.org/10.1177/0272989X221096070

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