New inhibitors of cathepsin V impair tumor cell proliferation and elastin degradation and increase immune cell cytotoxicity

Cathepsin V is a human lysosomal cysteine peptidase with specific functions during pathological processes and is as such a promising therapeutic target. Peptidase inhibitors represent powerful pharmacological tools for regulating excessive proteolytic activity in various diseases. Cathepsin V is hig...

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Detalles Bibliográficos
Autores principales: Mitrović, Ana, Senjor, Emanuela, Jukić, Marko, Bolčina, Lara, Prunk, Mateja, Proj, Matic, Nanut, Milica Perišić, Gobec, Stanislav, Kos, Janko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459403/
https://www.ncbi.nlm.nih.gov/pubmed/36147668
http://dx.doi.org/10.1016/j.csbj.2022.08.046

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