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Melatonin attenuates spatial learning and memory dysfunction in developing rats by suppressing isoflurane-induced endoplasmic reticulum stress via the SIRT1/Mfn2/PERK signaling pathway

Use of the inhalation anesthetic isoflurane may increase the risk of cognitive deficiency and neurotoxicity after birth. A growing body of evidence suggests that melatonin is an effective treatment for various types of oxidative stress damage and neurodegenerative disease. In this study, we aimed to...

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Detalles Bibliográficos
Autores principales:	Fang, Xi, Han, Qiang, Li, Shiyong, Luo, Ailin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459431/ https://www.ncbi.nlm.nih.gov/pubmed/36091956 http://dx.doi.org/10.1016/j.heliyon.2022.e10326

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