Cargando…

Melatonin attenuates spatial learning and memory dysfunction in developing rats by suppressing isoflurane-induced endoplasmic reticulum stress via the SIRT1/Mfn2/PERK signaling pathway

Use of the inhalation anesthetic isoflurane may increase the risk of cognitive deficiency and neurotoxicity after birth. A growing body of evidence suggests that melatonin is an effective treatment for various types of oxidative stress damage and neurodegenerative disease. In this study, we aimed to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fang, Xi, Han, Qiang, Li, Shiyong, Luo, Ailin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459431/ https://www.ncbi.nlm.nih.gov/pubmed/36091956 http://dx.doi.org/10.1016/j.heliyon.2022.e10326

Ejemplares similares

Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis
por: Yang, Qingling, et al.
Publicado: (2019)

Mfn2 Regulates High Glucose-Induced MAMs Dysfunction and Apoptosis in Podocytes via PERK Pathway
por: Cao, Yun, et al.
Publicado: (2021)

Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulum
por: McQuiston, Alexander, et al.
Publicado: (2017)

Impact of general anaesthesia on endoplasmic reticulum stress: propofol vs. isoflurane
por: Seo, Eun-Hye, et al.
Publicado: (2019)

PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy
por: Salaroglio, Iris C., et al.
Publicado: (2017)

Melatonin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress
por: Lin, Yu Wen, et al.
Publicado: (2018)

PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress
por: Romine, Isabelle C., et al.
Publicado: (2019)

Homer1a Attenuates Endoplasmic Reticulum Stress-Induced Mitochondrial Stress After Ischemic Reperfusion Injury by Inhibiting the PERK Pathway
por: Wei, Jialiang, et al.
Publicado: (2019)

Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling
por: Carrara, Marta, et al.
Publicado: (2015)

Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer
por: Qi, Jianjun, et al.
Publicado: (2020)

LRRK2 regulates endoplasmic reticulum–mitochondrial tethering through the PERK‐mediated ubiquitination pathway
por: Toyofuku, Toshihiko, et al.
Publicado: (2019)

Manganese activates autophagy to alleviate endoplasmic reticulum stress–induced apoptosis via PERK pathway
por: Liu, Chang, et al.
Publicado: (2019)

Melatonin attenuates palmitic acid-induced mouse granulosa cells apoptosis via endoplasmic reticulum stress
por: Chen, Zhi, et al.
Publicado: (2019)

FGF21 attenuates high uric acid-induced endoplasmic reticulum stress, inflammation and vascular endothelial cell dysfunction by activating Sirt1
por: Ouyang, Rong, et al.
Publicado: (2022)

Uncoupling Proteostasis and Development in Vitro with a Small Molecule Inhibitor of the Pancreatic Endoplasmic Reticulum Kinase, PERK
por: Harding, Heather P., et al.
Publicado: (2012)

The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress
por: Lebeau, Justine, et al.
Publicado: (2018)

Correction: Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer
por: Qi, Jianjun, et al.
Publicado: (2020)

Porcine parvovirus replication is suppressed by activation of the PERK signaling pathway and endoplasmic reticulum stress-mediated apoptosis
por: Cao, Liyan, et al.
Publicado: (2020)

Endoplasmic reticulum stress induces spatial memory deficits by activating GSK‐3
por: Lin, Li, et al.
Publicado: (2018)

A Systems Biological View of Life-and-Death Decision with Respect to Endoplasmic Reticulum Stress—The Role of PERK Pathway
por: Márton, Margita, et al.
Publicado: (2017)

Emodin mitigates podocytes apoptosis induced by endoplasmic reticulum stress through the inhibition of the PERK pathway in diabetic nephropathy
por: Tian, Nianxiu, et al.
Publicado: (2018)

Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress
por: Sundaram, Arunkumar, et al.
Publicado: (2018)

Endoplasmic Reticulum Stress Increases DUSP5 Expression via PERK-CHOP Pathway, Leading to Hepatocyte Death
por: Jo, Hye Jin, et al.
Publicado: (2019)

Endoplasmic Reticulum Stress in Colonic Mucosa of Ulcerative Colitis Patients Is Mediated by PERK and IRE1 Pathway Activation
por: Rodrigues, Bruno Lima, et al.
Publicado: (2022)

CPNE1 regulates myogenesis through the PERK-eIF2α pathway mediated by endoplasmic reticulum stress
por: Chen, Lin, et al.
Publicado: (2022)

Melatonin Can Modulate Neurodegenerative Diseases by Regulating Endoplasmic Reticulum Stress
por: Yoo, Yeong-Min, et al.
Publicado: (2023)

Atractylenolide III Attenuates Apoptosis in H9c2 Cells by Inhibiting Endoplasmic Reticulum Stress through the GRP78/PERK/CHOP Signaling Pathway
por: Zuo, Meng-yu, et al.
Publicado: (2022)

Increased Ca2 + transport across the mitochondria-associated membranes by Mfn2 inhibiting endoplasmic reticulum stress in ischemia/reperfusion kidney injury
por: Wang, Shun, et al.
Publicado: (2023)

c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration
por: Martinez, Alexis, et al.
Publicado: (2023)

Activation of the Protein Kinase R–Like Endoplasmic Reticulum Kinase (PERK) Pathway of the Unfolded Protein Response after Experimental Traumatic Brain Injury and Treatment with a PERK Inhibitor
por: Brady, Rhys D., et al.
Publicado: (2021)

Mfn2 Overexpression Attenuates MPTP Neurotoxicity In Vivo
por: Zhao, Fanpeng, et al.
Publicado: (2021)

Endoplasmic reticulum protein 5 attenuates platelet endoplasmic reticulum stress and secretion in a mouse model
por: Lay, Angelina J., et al.
Publicado: (2022)

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
por: Teske, Brian F., et al.
Publicado: (2011)

Endoplasmic Reticulum Stress Signaling Is Involved in Mitomycin C(MMC)-Induced Apoptosis in Human Fibroblasts via PERK Pathway
por: Shi, Kun, et al.
Publicado: (2013)

Endoplasmic reticulum stress promotes epithelial-mesenchymal transition via the PERK signaling pathway in paraquat-induced pulmonary fibrosis
por: Meng, Xiaoxiao, et al.
Publicado: (2021)

Toxoplasma gondii dense granule protein 3 promotes endoplasmic reticulum stress-induced apoptosis by activating the PERK pathway
por: Obed, Cudjoe, et al.
Publicado: (2022)

Gestational Exposure to Cyfluthrin through Endoplasmic Reticulum (ER) Stress—Mediated PERK Signaling Pathway Impairs Placental Development
por: Ni, Wensi, et al.
Publicado: (2022)

Knockout of PERK protects rat Müller glial cells against OGD-induced endoplasmic reticulum stress-related apoptosis
por: Wang, Xiaorui, et al.
Publicado: (2023)

Venlafaxine Attenuated the Cognitive and Memory Deficit in Mice Exposed to Isoflurane Alone
por: Li, Liang, et al.
Publicado: (2021)

Endoplasmic Reticulum-Based Calcium Dysfunctions in Synucleinopathies
por: Kovacs, Gergo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2ghahgubu6lrn01sjcbhclcb2n