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Atorvastatin Attenuates Radiotherapy-Induced Intestinal Damage through Activation of Autophagy and Antioxidant Effects
Abdominal or pelvic radiotherapy (RT) often results in small intestinal injury, such as apoptosis of epithelial cells and shortening of the villi. Atorvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, has many biological effects including cholesterol reduction, protection from c...
Autores principales: | Wei, Ming-Feng, Cheng, Ching-Hsueh, Wen, Shu-Yu, Lin, Jui-Chueh, Chen, Yu-Hsuan, Wang, Chun-Wei, Lee, Yi-Hsuan, Kuo, Sung-Hsin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459441/ https://www.ncbi.nlm.nih.gov/pubmed/36092168 http://dx.doi.org/10.1155/2022/7957255 |
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