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Clinical and MRI Donor-Site Outcomes After Autograft Harvesting From the Medial Trochlea for Talar Osteochondral Lesions: Minimum 5-Year Clinical Follow-up
BACKGROUND: Autologous osteochondral transplantation (AOT) is a treatment option for large or cystic osteochondral lesions of the talus (OLTs), with promising clinical results. However, donor-site morbidity (DSM) has always been a concern with this procedure. PURPOSE: To investigate the clinical and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459477/ https://www.ncbi.nlm.nih.gov/pubmed/36089925 http://dx.doi.org/10.1177/23259671221120075 |
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author | Guo, Changjun Li, Xingchen Zhu, Yuan Yang, Chonglin Xu, Xiangyang |
author_facet | Guo, Changjun Li, Xingchen Zhu, Yuan Yang, Chonglin Xu, Xiangyang |
author_sort | Guo, Changjun |
collection | PubMed |
description | BACKGROUND: Autologous osteochondral transplantation (AOT) is a treatment option for large or cystic osteochondral lesions of the talus (OLTs), with promising clinical results. However, donor-site morbidity (DSM) has always been a concern with this procedure. PURPOSE: To investigate the clinical and radiological outcomes of autograft harvesting from the medial trochlea for OLTs. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: A total of 46 consecutive patients were included after AOT procedures for OLTs, with donor autografts (single or double plugs) harvested from the medial trochlea of the ipsilateral knee. Lysholm scores were collected postoperatively at 12-month intervals to assess clinical outcomes. Postoperative magnetic resonance imaging (MRI) was used to assess the donor site using the MOCART (magnetic resonance observation of cartilage repair tissue) score. DSM was evaluated at 12-month intervals. Statistical analysis was performed to compare patients treated with single-plug and double-plug AOT procedures and establish whether there was any correlation between MOCART and Lysholm scores. RESULTS: The mean follow-up period was 98.3 months (range, 67-144 months). The Lysholm scores for all patients were 92.5 ± 6.1 and 99.9 ± 0.2 at the 12-month and final follow-ups, respectively. MRI of the donor sites was taken at an average of 93.8 ± 20.5 (range, 61-141) months postoperatively, and the mean MOCART score was 76.2 ± 4.9. The overall incidence of DSM in this study was 4.3% at 12 months, postoperatively, which decreased to 0% at the 24-month follow-up. There was no significant difference in either the Lysholm score (P = .16) or the MOCART score (P = .83) between the single-plug and double-plug groups at the final follow-up. There were no significant correlations between MOCART and Lysholm scores and patient age, number of grafts, or body mass index. CONCLUSION: According to the study findings, the DSM of donor autografts harvested from the medial trochlea was low, and the number (single or double) of grafts did not affect the functional outcome. |
format | Online Article Text |
id | pubmed-9459477 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-94594772022-09-10 Clinical and MRI Donor-Site Outcomes After Autograft Harvesting From the Medial Trochlea for Talar Osteochondral Lesions: Minimum 5-Year Clinical Follow-up Guo, Changjun Li, Xingchen Zhu, Yuan Yang, Chonglin Xu, Xiangyang Orthop J Sports Med Article BACKGROUND: Autologous osteochondral transplantation (AOT) is a treatment option for large or cystic osteochondral lesions of the talus (OLTs), with promising clinical results. However, donor-site morbidity (DSM) has always been a concern with this procedure. PURPOSE: To investigate the clinical and radiological outcomes of autograft harvesting from the medial trochlea for OLTs. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: A total of 46 consecutive patients were included after AOT procedures for OLTs, with donor autografts (single or double plugs) harvested from the medial trochlea of the ipsilateral knee. Lysholm scores were collected postoperatively at 12-month intervals to assess clinical outcomes. Postoperative magnetic resonance imaging (MRI) was used to assess the donor site using the MOCART (magnetic resonance observation of cartilage repair tissue) score. DSM was evaluated at 12-month intervals. Statistical analysis was performed to compare patients treated with single-plug and double-plug AOT procedures and establish whether there was any correlation between MOCART and Lysholm scores. RESULTS: The mean follow-up period was 98.3 months (range, 67-144 months). The Lysholm scores for all patients were 92.5 ± 6.1 and 99.9 ± 0.2 at the 12-month and final follow-ups, respectively. MRI of the donor sites was taken at an average of 93.8 ± 20.5 (range, 61-141) months postoperatively, and the mean MOCART score was 76.2 ± 4.9. The overall incidence of DSM in this study was 4.3% at 12 months, postoperatively, which decreased to 0% at the 24-month follow-up. There was no significant difference in either the Lysholm score (P = .16) or the MOCART score (P = .83) between the single-plug and double-plug groups at the final follow-up. There were no significant correlations between MOCART and Lysholm scores and patient age, number of grafts, or body mass index. CONCLUSION: According to the study findings, the DSM of donor autografts harvested from the medial trochlea was low, and the number (single or double) of grafts did not affect the functional outcome. SAGE Publications 2022-09-06 /pmc/articles/PMC9459477/ /pubmed/36089925 http://dx.doi.org/10.1177/23259671221120075 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Article Guo, Changjun Li, Xingchen Zhu, Yuan Yang, Chonglin Xu, Xiangyang Clinical and MRI Donor-Site Outcomes After Autograft Harvesting From the Medial Trochlea for Talar Osteochondral Lesions: Minimum 5-Year Clinical Follow-up |
title | Clinical and MRI Donor-Site Outcomes After Autograft Harvesting From
the Medial Trochlea for Talar Osteochondral Lesions: Minimum 5-Year Clinical
Follow-up |
title_full | Clinical and MRI Donor-Site Outcomes After Autograft Harvesting From
the Medial Trochlea for Talar Osteochondral Lesions: Minimum 5-Year Clinical
Follow-up |
title_fullStr | Clinical and MRI Donor-Site Outcomes After Autograft Harvesting From
the Medial Trochlea for Talar Osteochondral Lesions: Minimum 5-Year Clinical
Follow-up |
title_full_unstemmed | Clinical and MRI Donor-Site Outcomes After Autograft Harvesting From
the Medial Trochlea for Talar Osteochondral Lesions: Minimum 5-Year Clinical
Follow-up |
title_short | Clinical and MRI Donor-Site Outcomes After Autograft Harvesting From
the Medial Trochlea for Talar Osteochondral Lesions: Minimum 5-Year Clinical
Follow-up |
title_sort | clinical and mri donor-site outcomes after autograft harvesting from
the medial trochlea for talar osteochondral lesions: minimum 5-year clinical
follow-up |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459477/ https://www.ncbi.nlm.nih.gov/pubmed/36089925 http://dx.doi.org/10.1177/23259671221120075 |
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