Cargando…
Persistent Facial Blanching after Botulinum Toxin Injection
We report the case of a 38-year-old male patient who presented with blanching of the face after strenuous exercise or physical exertion. The symptoms regressed in a relaxed state. Three years before presentation, he underwent botulinum toxin injections in the affected areas of the face. Facial blanc...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459515/ https://www.ncbi.nlm.nih.gov/pubmed/36158853 http://dx.doi.org/10.1159/000525937 |
_version_ | 1784786528309870592 |
---|---|
author | Mitri, Fouad Kälber, Katharina Anna Enk, Alexander H. Toberer, Ferdinand |
author_facet | Mitri, Fouad Kälber, Katharina Anna Enk, Alexander H. Toberer, Ferdinand |
author_sort | Mitri, Fouad |
collection | PubMed |
description | We report the case of a 38-year-old male patient who presented with blanching of the face after strenuous exercise or physical exertion. The symptoms regressed in a relaxed state. Three years before presentation, he underwent botulinum toxin injections in the affected areas of the face. Facial blanching is a rare side effect of botulinum toxin injection. The postulated pathophysiology involves different transmitters mainly acetylcholine as well as co-transmitters implicated in vasodilation. Usually, facial blanching resolves shortly after waning of the botulinum toxin. However, in our case, the symptoms persisted for a longer time. Till date, therapy options for post-botulinum facial blanching are lacking, mainly due to the temporary aspect of the disease. |
format | Online Article Text |
id | pubmed-9459515 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-94595152022-09-23 Persistent Facial Blanching after Botulinum Toxin Injection Mitri, Fouad Kälber, Katharina Anna Enk, Alexander H. Toberer, Ferdinand Case Rep Dermatol Single Case We report the case of a 38-year-old male patient who presented with blanching of the face after strenuous exercise or physical exertion. The symptoms regressed in a relaxed state. Three years before presentation, he underwent botulinum toxin injections in the affected areas of the face. Facial blanching is a rare side effect of botulinum toxin injection. The postulated pathophysiology involves different transmitters mainly acetylcholine as well as co-transmitters implicated in vasodilation. Usually, facial blanching resolves shortly after waning of the botulinum toxin. However, in our case, the symptoms persisted for a longer time. Till date, therapy options for post-botulinum facial blanching are lacking, mainly due to the temporary aspect of the disease. S. Karger AG 2022-08-31 /pmc/articles/PMC9459515/ /pubmed/36158853 http://dx.doi.org/10.1159/000525937 Text en Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Single Case Mitri, Fouad Kälber, Katharina Anna Enk, Alexander H. Toberer, Ferdinand Persistent Facial Blanching after Botulinum Toxin Injection |
title | Persistent Facial Blanching after Botulinum Toxin Injection |
title_full | Persistent Facial Blanching after Botulinum Toxin Injection |
title_fullStr | Persistent Facial Blanching after Botulinum Toxin Injection |
title_full_unstemmed | Persistent Facial Blanching after Botulinum Toxin Injection |
title_short | Persistent Facial Blanching after Botulinum Toxin Injection |
title_sort | persistent facial blanching after botulinum toxin injection |
topic | Single Case |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459515/ https://www.ncbi.nlm.nih.gov/pubmed/36158853 http://dx.doi.org/10.1159/000525937 |
work_keys_str_mv | AT mitrifouad persistentfacialblanchingafterbotulinumtoxininjection AT kalberkatharinaanna persistentfacialblanchingafterbotulinumtoxininjection AT enkalexanderh persistentfacialblanchingafterbotulinumtoxininjection AT tobererferdinand persistentfacialblanchingafterbotulinumtoxininjection |