IgG4-Related Peripheral Neuropathy with Unilateral Cervical Nerve Root and Brachial Plexus Swelling: A Case Report

A 64-year-old man presented with left upper limb weakness and dysesthesia for 4 months. Magnetic resonance imaging demonstrated swelling from the 6th–8th left cervical nerve roots to the left brachial plexus. The serum IgG4 level was elevated (762.7 mg/dL). <sup>18</sup>F-FDG-PET showed...

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Autores principales: Tarisawa, Monami, Kano, Takahiro, Tanaka, Daiki, Yoshino, Masanao, Houzen, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Single Case − General Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459575/
https://www.ncbi.nlm.nih.gov/pubmed/36160654
http://dx.doi.org/10.1159/000525908
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author Tarisawa, Monami
Kano, Takahiro
Tanaka, Daiki
Yoshino, Masanao
Houzen, Hideki
author_facet Tarisawa, Monami
Kano, Takahiro
Tanaka, Daiki
Yoshino, Masanao
Houzen, Hideki
author_sort Tarisawa, Monami
collection PubMed
description A 64-year-old man presented with left upper limb weakness and dysesthesia for 4 months. Magnetic resonance imaging demonstrated swelling from the 6th–8th left cervical nerve roots to the left brachial plexus. The serum IgG4 level was elevated (762.7 mg/dL). <sup>18</sup>F-FDG-PET showed high uptake in the mediastinal lymph nodes, and biopsy revealed infiltration of IgG4-positive plasma cells. We diagnosed IgG4-related neuropathy, and steroid therapy administration improved the symptoms. IgG4-related disease should be considered in the differential diagnosis of peripheral nerve swellings. If biopsy of the disordered nerves is difficult, lymph nodes or other organs should be considered.
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spelling pubmed-94595752022-09-23 IgG4-Related Peripheral Neuropathy with Unilateral Cervical Nerve Root and Brachial Plexus Swelling: A Case Report Tarisawa, Monami Kano, Takahiro Tanaka, Daiki Yoshino, Masanao Houzen, Hideki Case Rep Neurol Single Case − General Neurology A 64-year-old man presented with left upper limb weakness and dysesthesia for 4 months. Magnetic resonance imaging demonstrated swelling from the 6th–8th left cervical nerve roots to the left brachial plexus. The serum IgG4 level was elevated (762.7 mg/dL). <sup>18</sup>F-FDG-PET showed high uptake in the mediastinal lymph nodes, and biopsy revealed infiltration of IgG4-positive plasma cells. We diagnosed IgG4-related neuropathy, and steroid therapy administration improved the symptoms. IgG4-related disease should be considered in the differential diagnosis of peripheral nerve swellings. If biopsy of the disordered nerves is difficult, lymph nodes or other organs should be considered. S. Karger AG 2022-08-16 /pmc/articles/PMC9459575/ /pubmed/36160654 http://dx.doi.org/10.1159/000525908 Text en Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case − General Neurology
Tarisawa, Monami
Kano, Takahiro
Tanaka, Daiki
Yoshino, Masanao
Houzen, Hideki
IgG4-Related Peripheral Neuropathy with Unilateral Cervical Nerve Root and Brachial Plexus Swelling: A Case Report
title IgG4-Related Peripheral Neuropathy with Unilateral Cervical Nerve Root and Brachial Plexus Swelling: A Case Report
title_full IgG4-Related Peripheral Neuropathy with Unilateral Cervical Nerve Root and Brachial Plexus Swelling: A Case Report
title_fullStr IgG4-Related Peripheral Neuropathy with Unilateral Cervical Nerve Root and Brachial Plexus Swelling: A Case Report
title_full_unstemmed IgG4-Related Peripheral Neuropathy with Unilateral Cervical Nerve Root and Brachial Plexus Swelling: A Case Report
title_short IgG4-Related Peripheral Neuropathy with Unilateral Cervical Nerve Root and Brachial Plexus Swelling: A Case Report
title_sort igg4-related peripheral neuropathy with unilateral cervical nerve root and brachial plexus swelling: a case report
topic Single Case − General Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459575/
https://www.ncbi.nlm.nih.gov/pubmed/36160654
http://dx.doi.org/10.1159/000525908
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