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Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma
Chronic myeloid leukemia (CML) is a hematologic malignancy that has significant improvement in its prognosis after the introduction of tyrosine kinase inhibitors. Transformation to accelerated phase or blast phase can happen. Myeloid sarcoma or chloroma is an uncommon extramedullary disease. It is v...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459602/ https://www.ncbi.nlm.nih.gov/pubmed/36157700 http://dx.doi.org/10.1159/000525767 |
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author | Ali, Elrazi A. Abu-Tineh, Mohammad Abdelrazek, Mohamed Petkar, Mahir Karzoun, Mzaki Subahi, Eihab A. Szabados, Lajos Yassin, Mohamed A. |
author_facet | Ali, Elrazi A. Abu-Tineh, Mohammad Abdelrazek, Mohamed Petkar, Mahir Karzoun, Mzaki Subahi, Eihab A. Szabados, Lajos Yassin, Mohamed A. |
author_sort | Ali, Elrazi A. |
collection | PubMed |
description | Chronic myeloid leukemia (CML) is a hematologic malignancy that has significant improvement in its prognosis after the introduction of tyrosine kinase inhibitors. Transformation to accelerated phase or blast phase can happen. Myeloid sarcoma or chloroma is an uncommon extramedullary disease. It is very unusual for patients with CML to develop myeloid sarcoma. We report a young man with CML in the chronic phase who developed myeloid sarcoma. There were many difficulties in the diagnosis of myeloid sarcoma due to the simulation of other more common conditions like infections and other malignancies. In addition, there are treatment challenges because of lack of standardized treatment. The case shed light on this rare complication, the challenging diagnosis, and its implication in patients with CML. |
format | Online Article Text |
id | pubmed-9459602 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-94596022022-09-23 Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma Ali, Elrazi A. Abu-Tineh, Mohammad Abdelrazek, Mohamed Petkar, Mahir Karzoun, Mzaki Subahi, Eihab A. Szabados, Lajos Yassin, Mohamed A. Case Rep Oncol Case Report Chronic myeloid leukemia (CML) is a hematologic malignancy that has significant improvement in its prognosis after the introduction of tyrosine kinase inhibitors. Transformation to accelerated phase or blast phase can happen. Myeloid sarcoma or chloroma is an uncommon extramedullary disease. It is very unusual for patients with CML to develop myeloid sarcoma. We report a young man with CML in the chronic phase who developed myeloid sarcoma. There were many difficulties in the diagnosis of myeloid sarcoma due to the simulation of other more common conditions like infections and other malignancies. In addition, there are treatment challenges because of lack of standardized treatment. The case shed light on this rare complication, the challenging diagnosis, and its implication in patients with CML. S. Karger AG 2022-08-30 /pmc/articles/PMC9459602/ /pubmed/36157700 http://dx.doi.org/10.1159/000525767 Text en Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Case Report Ali, Elrazi A. Abu-Tineh, Mohammad Abdelrazek, Mohamed Petkar, Mahir Karzoun, Mzaki Subahi, Eihab A. Szabados, Lajos Yassin, Mohamed A. Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma |
title | Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma |
title_full | Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma |
title_fullStr | Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma |
title_full_unstemmed | Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma |
title_short | Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma |
title_sort | myeloid sarcoma mimicking dental abscess in a patient with chronic myeloid leukemia: diagnostic and therapeutic dilemma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459602/ https://www.ncbi.nlm.nih.gov/pubmed/36157700 http://dx.doi.org/10.1159/000525767 |
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