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Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma

Chronic myeloid leukemia (CML) is a hematologic malignancy that has significant improvement in its prognosis after the introduction of tyrosine kinase inhibitors. Transformation to accelerated phase or blast phase can happen. Myeloid sarcoma or chloroma is an uncommon extramedullary disease. It is v...

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Autores principales: Ali, Elrazi A., Abu-Tineh, Mohammad, Abdelrazek, Mohamed, Petkar, Mahir, Karzoun, Mzaki, Subahi, Eihab A., Szabados, Lajos, Yassin, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459602/
https://www.ncbi.nlm.nih.gov/pubmed/36157700
http://dx.doi.org/10.1159/000525767
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author Ali, Elrazi A.
Abu-Tineh, Mohammad
Abdelrazek, Mohamed
Petkar, Mahir
Karzoun, Mzaki
Subahi, Eihab A.
Szabados, Lajos
Yassin, Mohamed A.
author_facet Ali, Elrazi A.
Abu-Tineh, Mohammad
Abdelrazek, Mohamed
Petkar, Mahir
Karzoun, Mzaki
Subahi, Eihab A.
Szabados, Lajos
Yassin, Mohamed A.
author_sort Ali, Elrazi A.
collection PubMed
description Chronic myeloid leukemia (CML) is a hematologic malignancy that has significant improvement in its prognosis after the introduction of tyrosine kinase inhibitors. Transformation to accelerated phase or blast phase can happen. Myeloid sarcoma or chloroma is an uncommon extramedullary disease. It is very unusual for patients with CML to develop myeloid sarcoma. We report a young man with CML in the chronic phase who developed myeloid sarcoma. There were many difficulties in the diagnosis of myeloid sarcoma due to the simulation of other more common conditions like infections and other malignancies. In addition, there are treatment challenges because of lack of standardized treatment. The case shed light on this rare complication, the challenging diagnosis, and its implication in patients with CML.
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spelling pubmed-94596022022-09-23 Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma Ali, Elrazi A. Abu-Tineh, Mohammad Abdelrazek, Mohamed Petkar, Mahir Karzoun, Mzaki Subahi, Eihab A. Szabados, Lajos Yassin, Mohamed A. Case Rep Oncol Case Report Chronic myeloid leukemia (CML) is a hematologic malignancy that has significant improvement in its prognosis after the introduction of tyrosine kinase inhibitors. Transformation to accelerated phase or blast phase can happen. Myeloid sarcoma or chloroma is an uncommon extramedullary disease. It is very unusual for patients with CML to develop myeloid sarcoma. We report a young man with CML in the chronic phase who developed myeloid sarcoma. There were many difficulties in the diagnosis of myeloid sarcoma due to the simulation of other more common conditions like infections and other malignancies. In addition, there are treatment challenges because of lack of standardized treatment. The case shed light on this rare complication, the challenging diagnosis, and its implication in patients with CML. S. Karger AG 2022-08-30 /pmc/articles/PMC9459602/ /pubmed/36157700 http://dx.doi.org/10.1159/000525767 Text en Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Ali, Elrazi A.
Abu-Tineh, Mohammad
Abdelrazek, Mohamed
Petkar, Mahir
Karzoun, Mzaki
Subahi, Eihab A.
Szabados, Lajos
Yassin, Mohamed A.
Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma
title Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma
title_full Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma
title_fullStr Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma
title_full_unstemmed Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma
title_short Myeloid Sarcoma Mimicking Dental Abscess in a Patient with Chronic Myeloid Leukemia: Diagnostic and Therapeutic Dilemma
title_sort myeloid sarcoma mimicking dental abscess in a patient with chronic myeloid leukemia: diagnostic and therapeutic dilemma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459602/
https://www.ncbi.nlm.nih.gov/pubmed/36157700
http://dx.doi.org/10.1159/000525767
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