Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers

For this study, new dendrimers were prepared from poly(propylene imine) (PPI) and polyamidoamine (PAMAM) dendrimers using an efficient acid-base reaction with various phenolic acids. The syntheses were also optimized in both microwave and microfluidic reactors. These ionic and hydrophilic dendrimers...

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Autores principales: Bacha, Katia, Estager, Julien, Brassart-Pasco, Sylvie, Chemotti, Catherine, Fernandes, Antony E., Mbakidi, Jean-Pierre, Deleu, Magali, Bouquillon, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459880/
https://www.ncbi.nlm.nih.gov/pubmed/36080588
http://dx.doi.org/10.3390/polym14173513
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author Bacha, Katia
Estager, Julien
Brassart-Pasco, Sylvie
Chemotti, Catherine
Fernandes, Antony E.
Mbakidi, Jean-Pierre
Deleu, Magali
Bouquillon, Sandrine
author_facet Bacha, Katia
Estager, Julien
Brassart-Pasco, Sylvie
Chemotti, Catherine
Fernandes, Antony E.
Mbakidi, Jean-Pierre
Deleu, Magali
Bouquillon, Sandrine
author_sort Bacha, Katia
collection PubMed
description For this study, new dendrimers were prepared from poly(propylene imine) (PPI) and polyamidoamine (PAMAM) dendrimers using an efficient acid-base reaction with various phenolic acids. The syntheses were also optimized in both microwave and microfluidic reactors. These ionic and hydrophilic dendrimers were fully characterized and showed excellent antioxidant properties. Their cytotoxic properties have been also determined in the case of fibroblast dermal cells.
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spelling pubmed-94598802022-09-10 Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers Bacha, Katia Estager, Julien Brassart-Pasco, Sylvie Chemotti, Catherine Fernandes, Antony E. Mbakidi, Jean-Pierre Deleu, Magali Bouquillon, Sandrine Polymers (Basel) Article For this study, new dendrimers were prepared from poly(propylene imine) (PPI) and polyamidoamine (PAMAM) dendrimers using an efficient acid-base reaction with various phenolic acids. The syntheses were also optimized in both microwave and microfluidic reactors. These ionic and hydrophilic dendrimers were fully characterized and showed excellent antioxidant properties. Their cytotoxic properties have been also determined in the case of fibroblast dermal cells. MDPI 2022-08-27 /pmc/articles/PMC9459880/ /pubmed/36080588 http://dx.doi.org/10.3390/polym14173513 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bacha, Katia
Estager, Julien
Brassart-Pasco, Sylvie
Chemotti, Catherine
Fernandes, Antony E.
Mbakidi, Jean-Pierre
Deleu, Magali
Bouquillon, Sandrine
Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers
title Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers
title_full Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers
title_fullStr Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers
title_full_unstemmed Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers
title_short Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers
title_sort synthesis and activity of ionic antioxidant-functionalized pamams and ppis dendrimers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459880/
https://www.ncbi.nlm.nih.gov/pubmed/36080588
http://dx.doi.org/10.3390/polym14173513
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