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Hyaluronic Acid: A Review of the Drug Delivery Capabilities of This Naturally Occurring Polysaccharide
The inclusion of physiologically active molecules into a naturally occurring polymer matrix can improve the degradation, absorption, and release profile of the drug, thus boosting the therapeutic impact and potentially even reducing the frequency of administration. The human body produces significan...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460006/ https://www.ncbi.nlm.nih.gov/pubmed/36080515 http://dx.doi.org/10.3390/polym14173442 |
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author | Buckley, Ciara Murphy, Emma J. Montgomery, Therese R. Major, Ian |
author_facet | Buckley, Ciara Murphy, Emma J. Montgomery, Therese R. Major, Ian |
author_sort | Buckley, Ciara |
collection | PubMed |
description | The inclusion of physiologically active molecules into a naturally occurring polymer matrix can improve the degradation, absorption, and release profile of the drug, thus boosting the therapeutic impact and potentially even reducing the frequency of administration. The human body produces significant amounts of polysaccharide hyaluronic acid, which boasts exceptional biocompatibility, biodegradability, and one-of-a-kind physicochemical features. In this review, we will examine the clinical trials currently utilizing hyaluronic acid and address the bright future of this versatile polymer, as well as summarize the numerous applications of hyaluronic acid in drug delivery and immunomodulation. |
format | Online Article Text |
id | pubmed-9460006 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94600062022-09-10 Hyaluronic Acid: A Review of the Drug Delivery Capabilities of This Naturally Occurring Polysaccharide Buckley, Ciara Murphy, Emma J. Montgomery, Therese R. Major, Ian Polymers (Basel) Review The inclusion of physiologically active molecules into a naturally occurring polymer matrix can improve the degradation, absorption, and release profile of the drug, thus boosting the therapeutic impact and potentially even reducing the frequency of administration. The human body produces significant amounts of polysaccharide hyaluronic acid, which boasts exceptional biocompatibility, biodegradability, and one-of-a-kind physicochemical features. In this review, we will examine the clinical trials currently utilizing hyaluronic acid and address the bright future of this versatile polymer, as well as summarize the numerous applications of hyaluronic acid in drug delivery and immunomodulation. MDPI 2022-08-23 /pmc/articles/PMC9460006/ /pubmed/36080515 http://dx.doi.org/10.3390/polym14173442 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Buckley, Ciara Murphy, Emma J. Montgomery, Therese R. Major, Ian Hyaluronic Acid: A Review of the Drug Delivery Capabilities of This Naturally Occurring Polysaccharide |
title | Hyaluronic Acid: A Review of the Drug Delivery Capabilities of This Naturally Occurring Polysaccharide |
title_full | Hyaluronic Acid: A Review of the Drug Delivery Capabilities of This Naturally Occurring Polysaccharide |
title_fullStr | Hyaluronic Acid: A Review of the Drug Delivery Capabilities of This Naturally Occurring Polysaccharide |
title_full_unstemmed | Hyaluronic Acid: A Review of the Drug Delivery Capabilities of This Naturally Occurring Polysaccharide |
title_short | Hyaluronic Acid: A Review of the Drug Delivery Capabilities of This Naturally Occurring Polysaccharide |
title_sort | hyaluronic acid: a review of the drug delivery capabilities of this naturally occurring polysaccharide |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460006/ https://www.ncbi.nlm.nih.gov/pubmed/36080515 http://dx.doi.org/10.3390/polym14173442 |
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