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Exploration of metabolic responses towards hypoxia mimetic DMOG in cancer cells by using untargeted metabolomics

Hypoxia is considered as one of the most crucial elements of tumor microenvironment. The hypoxia inducible transcription factors (HIF-1/2) are used by the cancer cells to adapt hypoxic microenvironment through regulating the expression of various target genes, including metabolic enzymes. Dimethylox...

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Detalles Bibliográficos
Autor principal: Imran Khan, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460158/
https://www.ncbi.nlm.nih.gov/pubmed/36091722
http://dx.doi.org/10.1016/j.sjbs.2022.103426