Cargando…

Yin and yang of cannabinoid CB1 receptor: CB1 deletion in immune cells causes exacerbation while deletion in non-immune cells attenuates obesity

While blockade of cannabinoid receptor 1 (CB1) has been shown to attenuate diet-induced obesity (DIO), its relative role in different cell types has not been tested. The current study investigated the role of CB1 in immune vs non-immune cells during DIO by generating radiation-induced bone marrow ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miranda, Kathryn, Becker, William, Busbee, Philip B., Dopkins, Nicholas, Abdulla, Osama A., Zhong, Yin, Zhang, Jiajia, Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460165/ https://www.ncbi.nlm.nih.gov/pubmed/36093055 http://dx.doi.org/10.1016/j.isci.2022.104994

Ejemplares similares

Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity
por: Mehrpouya-Bahrami, Pegah, et al.
Publicado: (2017)

Cannabigerol Action at Cannabinoid CB(1) and CB(2) Receptors and at CB(1)–CB(2) Heteroreceptor Complexes
por: Navarro, Gemma, et al.
Publicado: (2018)

Effects of pro‐inflammatory cytokines on cannabinoid CB (1) and CB (2) receptors in immune cells
por: Jean‐Gilles, L., et al.
Publicado: (2015)

Cannabinoid CB(1) and CB(2) Receptor Signaling and Bias
por: Ibsen, Mikkel Søes, et al.
Publicado: (2017)

Dichotomic Hippocampal Transcriptome After Glutamatergic vs. GABAergic Deletion of the Cannabinoid CB1 Receptor
por: Pascual Cuadrado, Diego, et al.
Publicado: (2021)

Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction
por: Fish, Eric W., et al.
Publicado: (2019)

Cannabinoid CB1 Receptor Deletion from Catecholaminergic Neurons Protects from Diet-Induced Obesity
por: Srivastava, Raj Kamal, et al.
Publicado: (2022)

AhR Activation Leads to Alterations in the Gut Microbiome with Consequent Effect on Induction of Myeloid Derived Suppressor Cells in a CXCR2-Dependent Manner
por: Neamah, Wurood Hantoosh, et al.
Publicado: (2020)

Natural Indoles, Indole-3-Carbinol (I3C) and 3,3’-Diindolylmethane (DIM), Attenuate Staphylococcal Enterotoxin B-Mediated Liver Injury by Downregulating miR-31 Expression and Promoting Caspase-2-Mediated Apoptosis
por: Busbee, Philip B., et al.
Publicado: (2015)

The Structure–Function Relationships of Classical Cannabinoids: CB1/CB2 Modulation
por: Bow, Eric W., et al.
Publicado: (2016)

Epigenetic Regulation of Cannabinoid-Mediated Attenuation of Inflammation and Its Impact on the Use of Cannabinoids to Treat Autoimmune Diseases
por: Holloman, Bryan Latrell, et al.
Publicado: (2021)

Cannabinoid Receptors CB1 and CB2 Modulate the Electroretinographic Waves in Vervet Monkeys
por: Bouskila, Joseph, et al.
Publicado: (2016)

Cannabinoid CB1 receptors regulate salivation
por: Andreis, Kelsey, et al.
Publicado: (2022)

Voltage dependence of the cannabinoid CB1 receptor
por: Goldberger, Esty, et al.
Publicado: (2022)

Role of Gut Microbiota in Cannabinoid-Mediated Suppression of Inflammation
por: Varsha, Kontham Kulangara, et al.
Publicado: (2022)

AhR Activation Leads to Attenuation of Murine Autoimmune Hepatitis: Single-Cell RNA-Seq Analysis Reveals Unique Immune Cell Phenotypes and Gene Expression Changes in the Liver
por: Cannon, Alkeiver S., et al.
Publicado: (2022)

Expression and Function of Cannabinoid Receptors CB1 and CB2 and Their Cognate Cannabinoid Ligands in Murine Embryonic Stem Cells
por: Jiang, Shuxian, et al.
Publicado: (2007)

Positive Allosteric Modulation of CB1 and CB2 Cannabinoid Receptors Enhances the Neuroprotective Activity of a Dual CB1R/CB2R Orthosteric Agonist
por: Polini, Beatrice, et al.
Publicado: (2020)

Cannabinoids Modulate Neuronal Activity and Cancer by CB1 and CB2 Receptor-Independent Mechanisms
por: Soderstrom, Ken, et al.
Publicado: (2017)

The Ability of AhR Ligands to Attenuate Delayed Type Hypersensitivity Reaction Is Associated With Alterations in the Gut Microbiota
por: Abdulla, Osama A., et al.
Publicado: (2021)

Use of Cannabinoids to Treat Acute Respiratory Distress Syndrome and Cytokine Storm Associated with Coronavirus Disease-2019
por: Nagarkatti, Prakash, et al.
Publicado: (2020)

CB1 Cannabinoid Receptor Signaling and Biased Signaling
por: Leo, Luciana M., et al.
Publicado: (2021)

An Update on Non-CB(1), Non-CB(2) Cannabinoid Related G-Protein-Coupled Receptors
por: Morales, Paula, et al.
Publicado: (2017)

Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence
por: Ibsen, Mikkel Søes, et al.
Publicado: (2019)

Tricyclic Pyrazole-Based Compounds as Useful Scaffolds for Cannabinoid CB(1)/CB(2) Receptor Interaction
por: Asproni, Battistina, et al.
Publicado: (2021)

Tryptamine Attenuates Experimental Multiple Sclerosis Through Activation of Aryl Hydrocarbon Receptor
por: Dopkins, Nicholas, et al.
Publicado: (2021)

The Yin and Yang of Innate Immunity in Stroke
por: Xu, Xiaomeng, et al.
Publicado: (2014)

Coupling of CB-2 and CB-1
por: Ansaldo
Publicado: (2003)

Cannabinoid Receptor 1 Blockade Attenuates Obesity and Adipose Tissue Type 1 Inflammation Through miR-30e-5p Regulation of Delta-Like-4 in Macrophages and Consequently Downregulation of Th1 Cells
por: Miranda, Kathryn, et al.
Publicado: (2019)

Functional characterization of the novel cannabinoid receptor GPR55 and its modulation by CB(1 )and CB(2 )receptors
por: Balenga, Nariman, et al.
Publicado: (2008)

Clinical Significance of Cannabinoid Receptors CB1 and CB2 Expression in Human Malignant and Benign Thyroid Lesions
por: Lakiotaki, Eleftheria, et al.
Publicado: (2015)

Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity
por: Franks, Lirit N., et al.
Publicado: (2016)

Evaluation of carboxamide-type synthetic cannabinoids as CB(1)/CB(2) receptor agonists: difference between the enantiomers
por: Doi, Takahiro, et al.
Publicado: (2017)

Effects of Cocaine Self-Administration and Its Extinction on the Rat Brain Cannabinoid CB1 and CB2 Receptors
por: Bystrowska, Beata, et al.
Publicado: (2018)

Loss of Cannabinoid Receptor CB1 Induces Preterm Birth
por: Wang, Haibin, et al.
Publicado: (2008)

Increased Expression of Cannabinoid CB(1) Receptors in Achilles Tendinosis
por: Björklund, Emmelie, et al.
Publicado: (2011)

Cannabinoid CB(1) Receptors Mediate the Gastroprotective Effect of Neurotensin
por: Hassanzadeh, Parichehr, et al.
Publicado: (2012)

Cardiorespiratory Anomalies in Mice Lacking CB(1) Cannabinoid Receptors
por: Silvani, Alessandro, et al.
Publicado: (2014)

THC Regulates Tearing via Cannabinoid CB1 Receptors
por: Thayer, Amanda, et al.
Publicado: (2020)

Endocannabinoid Anandamide Attenuates Acute Respiratory Distress Syndrome through Modulation of Microbiome in the Gut-Lung Axis
por: Sultan, Muthanna, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i3nvbmmk60kq5osa9kleks3q14