Icaritin inhibits CDK2 expression and activity to interfere with tumor progression

Icaritin has shown antitumor activity in a variety of human solid tumors and myeloid leukemia cells. However, the direct target of icaritin and the underlying mechanisms remain unclear. In our study, CDK2 was found to be a direct target of icaritin in tumor cells. On one hand, icaritin interacted wi...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Wang, Xin, Zhang, Chuanbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460166/
https://www.ncbi.nlm.nih.gov/pubmed/36093042
http://dx.doi.org/10.1016/j.isci.2022.104991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460166/
https://www.ncbi.nlm.nih.gov/pubmed/36093042
http://dx.doi.org/10.1016/j.isci.2022.104991

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