Cargando…
Icaritin inhibits CDK2 expression and activity to interfere with tumor progression
Icaritin has shown antitumor activity in a variety of human solid tumors and myeloid leukemia cells. However, the direct target of icaritin and the underlying mechanisms remain unclear. In our study, CDK2 was found to be a direct target of icaritin in tumor cells. On one hand, icaritin interacted wi...
Autores principales: | Zhang, Chao, Wang, Xin, Zhang, Chuanbao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460166/ https://www.ncbi.nlm.nih.gov/pubmed/36093042 http://dx.doi.org/10.1016/j.isci.2022.104991 |
Ejemplares similares
-
Icaritin inhibits decidualization of endometrial stromal cells
por: Le, Aiwen, et al.
Publicado: (2017) -
Icaritin Reduces Oral Squamous Cell Carcinoma Progression via the Inhibition of STAT3 Signaling
por: Yang, Jian-Guang, et al.
Publicado: (2017) -
A comparative study on the in vitro and in vivo antitumor efficacy of icaritin and hydrous icaritin nanorods
por: Li, Haowen, et al.
Publicado: (2020) -
Icaritin Inhibits JAK/STAT3 Signaling and Growth of Renal Cell Carcinoma
por: Li, Shasha, et al.
Publicado: (2013) -
Icaritin promotes apoptosis and inhibits proliferation by down-regulating AFP gene expression in hepatocellular carcinoma
por: Li, Hui, et al.
Publicado: (2021)