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Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis

The HeartPy Python toolkit for analysis of noisy signals from heart rate measurements is an excellent tool to use in conjunction with novel wearable sensors. Nevertheless, most of the work to date has focused on applying the toolkit to data measured with commercially available sensors. We demonstrat...

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Autores principales: Vićentić, Teodora, Rašljić Rafajilović, Milena, Ilić, Stefan D., Koteska, Bojana, Madevska Bogdanova, Ana, Pašti, Igor A., Lehocki, Fedor, Spasenović, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460202/
https://www.ncbi.nlm.nih.gov/pubmed/36080785
http://dx.doi.org/10.3390/s22176326
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author Vićentić, Teodora
Rašljić Rafajilović, Milena
Ilić, Stefan D.
Koteska, Bojana
Madevska Bogdanova, Ana
Pašti, Igor A.
Lehocki, Fedor
Spasenović, Marko
author_facet Vićentić, Teodora
Rašljić Rafajilović, Milena
Ilić, Stefan D.
Koteska, Bojana
Madevska Bogdanova, Ana
Pašti, Igor A.
Lehocki, Fedor
Spasenović, Marko
author_sort Vićentić, Teodora
collection PubMed
description The HeartPy Python toolkit for analysis of noisy signals from heart rate measurements is an excellent tool to use in conjunction with novel wearable sensors. Nevertheless, most of the work to date has focused on applying the toolkit to data measured with commercially available sensors. We demonstrate the application of the HeartPy functions to data obtained with a novel graphene-based heartbeat sensor. We produce the sensor by laser-inducing graphene on a flexible polyimide substrate. Both graphene on the polyimide substrate and graphene transferred onto a PDMS substrate show piezoresistive behavior that can be utilized to measure human heartbeat by registering median cubital vein motion during blood pumping. We process electrical resistance data from the graphene sensor using HeartPy and demonstrate extraction of several heartbeat parameters, in agreement with measurements taken with independent reference sensors. We compare the quality of the heartbeat signal from graphene on different substrates, demonstrating that in all cases the device yields results consistent with reference sensors. Our work is a first demonstration of successful application of HeartPy to analysis of data from a sensor in development.
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spelling pubmed-94602022022-09-10 Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis Vićentić, Teodora Rašljić Rafajilović, Milena Ilić, Stefan D. Koteska, Bojana Madevska Bogdanova, Ana Pašti, Igor A. Lehocki, Fedor Spasenović, Marko Sensors (Basel) Article The HeartPy Python toolkit for analysis of noisy signals from heart rate measurements is an excellent tool to use in conjunction with novel wearable sensors. Nevertheless, most of the work to date has focused on applying the toolkit to data measured with commercially available sensors. We demonstrate the application of the HeartPy functions to data obtained with a novel graphene-based heartbeat sensor. We produce the sensor by laser-inducing graphene on a flexible polyimide substrate. Both graphene on the polyimide substrate and graphene transferred onto a PDMS substrate show piezoresistive behavior that can be utilized to measure human heartbeat by registering median cubital vein motion during blood pumping. We process electrical resistance data from the graphene sensor using HeartPy and demonstrate extraction of several heartbeat parameters, in agreement with measurements taken with independent reference sensors. We compare the quality of the heartbeat signal from graphene on different substrates, demonstrating that in all cases the device yields results consistent with reference sensors. Our work is a first demonstration of successful application of HeartPy to analysis of data from a sensor in development. MDPI 2022-08-23 /pmc/articles/PMC9460202/ /pubmed/36080785 http://dx.doi.org/10.3390/s22176326 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vićentić, Teodora
Rašljić Rafajilović, Milena
Ilić, Stefan D.
Koteska, Bojana
Madevska Bogdanova, Ana
Pašti, Igor A.
Lehocki, Fedor
Spasenović, Marko
Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
title Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
title_full Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
title_fullStr Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
title_full_unstemmed Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
title_short Laser-Induced Graphene for Heartbeat Monitoring with HeartPy Analysis
title_sort laser-induced graphene for heartbeat monitoring with heartpy analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460202/
https://www.ncbi.nlm.nih.gov/pubmed/36080785
http://dx.doi.org/10.3390/s22176326
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