A new fluorescent sensor mitoferrofluor indicates the presence of chelatable iron in polarized and depolarized mitochondria

Mitochondrial chelatable iron contributes to the severity of several injury processes, including ischemia/reperfusion, oxidative stress, and drug toxicity. However, methods to measure this species in living cells are lacking. To measure mitochondrial chelatable iron in living cells, here we synthesi...

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Detalles Bibliográficos
Autores principales: Kholmukhamedov, Andaleb, Li, Li, Lindsey, Christopher C., Hu, Jiangting, Nieminen, Anna-Liisa, Takemoto, Kenji, Beeson, Gyda C., Beneker, Chad M., McInnes, Campbell, Beeson, Craig C., Lemasters, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460511/
https://www.ncbi.nlm.nih.gov/pubmed/35931111
http://dx.doi.org/10.1016/j.jbc.2022.102336

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