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Phosphomimetic Dicer S1016E triggers a switch to glutamine metabolism in gemcitabine-resistant pancreatic cancer

OBJECTIVE: Dicer is an enzyme that processes microRNAs (miRNAs) precursors into mature miRNAs, which have been implicated in various aspects of cancer progressions, such as clinical aggressiveness, prognosis, and survival outcomes. We previously showed that high expression of Dicer is associated wit...

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Detalles Bibliográficos
Autores principales: Park, Ji Min, Peng, Jei-Ming, Shen, Yu-Shiuan, Lin, Chia-Ying, Hsu, Tung-Wei, Su, Yen-Hao, Chen, Hsin-An, Saengboonmee, Charupong, Chang, Jung-Su, Chiu, Ching-Feng, Shan, Yan-Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460536/
https://www.ncbi.nlm.nih.gov/pubmed/35995401
http://dx.doi.org/10.1016/j.molmet.2022.101576

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