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A Proinflammatory Diet Is Associated with Higher Risk of Peripheral Artery Disease
Peripheral arterial disease (PAD) has a strong relationship with inflammation. However, it is unclear whether the dietary inflammatory potential is associated with PAD. We aimed to address this knowledge gap. The dietary inflammatory index (DII) was obtained using a 24-h dietary recall interview for...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460607/ https://www.ncbi.nlm.nih.gov/pubmed/36079748 http://dx.doi.org/10.3390/nu14173490 |
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author | Fan, Heze Zhou, Juan Huang, Yuzhi Feng, Xueying Dang, Peizhu Li, Guoliang Yuan, Zuyi |
author_facet | Fan, Heze Zhou, Juan Huang, Yuzhi Feng, Xueying Dang, Peizhu Li, Guoliang Yuan, Zuyi |
author_sort | Fan, Heze |
collection | PubMed |
description | Peripheral arterial disease (PAD) has a strong relationship with inflammation. However, it is unclear whether the dietary inflammatory potential is associated with PAD. We aimed to address this knowledge gap. The dietary inflammatory index (DII) was obtained using a 24-h dietary recall interview for each individual. Logistic regression models and restricted cubic spline were performed to assess the relationship of DII with the prevalence of PAD. In addition, Spearman correlation analysis and subgroup analysis were also undertaken. In total, 5840 individuals from the 1999–2004 National Health and Nutrition Examination Survey (NHANES) were enrolled in our study. Participants in higher DII quartile tended to have higher rates of PAD. The increase in DII scores showed a positive association with PAD after fully multivariate adjustment (OR (odds ratios) = 1.094, 95% confidence interval (CI): 1.022–1.171). The multivariable-adjusted OR and 95% CI of the highest DII index quartile compared with the lowest quartile was 1.543 (95% CI: 1.116–2.133). Subgroup analysis demonstrated that the positive association between DII and PAD was persistent across population subgroups. In conclusion, we report that a proinflammatory dietary pattern is related to a higher risk of developing PAD among US adults. |
format | Online Article Text |
id | pubmed-9460607 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94606072022-09-10 A Proinflammatory Diet Is Associated with Higher Risk of Peripheral Artery Disease Fan, Heze Zhou, Juan Huang, Yuzhi Feng, Xueying Dang, Peizhu Li, Guoliang Yuan, Zuyi Nutrients Article Peripheral arterial disease (PAD) has a strong relationship with inflammation. However, it is unclear whether the dietary inflammatory potential is associated with PAD. We aimed to address this knowledge gap. The dietary inflammatory index (DII) was obtained using a 24-h dietary recall interview for each individual. Logistic regression models and restricted cubic spline were performed to assess the relationship of DII with the prevalence of PAD. In addition, Spearman correlation analysis and subgroup analysis were also undertaken. In total, 5840 individuals from the 1999–2004 National Health and Nutrition Examination Survey (NHANES) were enrolled in our study. Participants in higher DII quartile tended to have higher rates of PAD. The increase in DII scores showed a positive association with PAD after fully multivariate adjustment (OR (odds ratios) = 1.094, 95% confidence interval (CI): 1.022–1.171). The multivariable-adjusted OR and 95% CI of the highest DII index quartile compared with the lowest quartile was 1.543 (95% CI: 1.116–2.133). Subgroup analysis demonstrated that the positive association between DII and PAD was persistent across population subgroups. In conclusion, we report that a proinflammatory dietary pattern is related to a higher risk of developing PAD among US adults. MDPI 2022-08-25 /pmc/articles/PMC9460607/ /pubmed/36079748 http://dx.doi.org/10.3390/nu14173490 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Fan, Heze Zhou, Juan Huang, Yuzhi Feng, Xueying Dang, Peizhu Li, Guoliang Yuan, Zuyi A Proinflammatory Diet Is Associated with Higher Risk of Peripheral Artery Disease |
title | A Proinflammatory Diet Is Associated with Higher Risk of Peripheral Artery Disease |
title_full | A Proinflammatory Diet Is Associated with Higher Risk of Peripheral Artery Disease |
title_fullStr | A Proinflammatory Diet Is Associated with Higher Risk of Peripheral Artery Disease |
title_full_unstemmed | A Proinflammatory Diet Is Associated with Higher Risk of Peripheral Artery Disease |
title_short | A Proinflammatory Diet Is Associated with Higher Risk of Peripheral Artery Disease |
title_sort | proinflammatory diet is associated with higher risk of peripheral artery disease |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460607/ https://www.ncbi.nlm.nih.gov/pubmed/36079748 http://dx.doi.org/10.3390/nu14173490 |
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