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Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market
One way of increasing folate status, especially in a state of increased demand (e.g., women of childbearing age), is dietary supplementation with folic acid (FA). The dietary supplements market in Poland shows a controversial situation and, for many reasons (the ease of placing them on the market, t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460679/ https://www.ncbi.nlm.nih.gov/pubmed/36079757 http://dx.doi.org/10.3390/nu14173500 |
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author | Czarnowska-Kujawska, Marta Klepacka, Joanna Zielińska, Olga Samaniego-Vaesken, María de Lourdes |
author_facet | Czarnowska-Kujawska, Marta Klepacka, Joanna Zielińska, Olga Samaniego-Vaesken, María de Lourdes |
author_sort | Czarnowska-Kujawska, Marta |
collection | PubMed |
description | One way of increasing folate status, especially in a state of increased demand (e.g., women of childbearing age), is dietary supplementation with folic acid (FA). The dietary supplements market in Poland shows a controversial situation and, for many reasons (the ease of placing them on the market, the lack of control of chemical composition), the possibility of inaccurate information provided on the supplement’s label arises. We questioned whether FA supplements available in Poland are indeed complying with regulations and if they could actually improve folate status amongst the target population groups consuming them. Almost 500 products containing FA were identified and available for sale in pharmacies, all of them including specific information provided by manufacturers on the packaging, such as the amount of FA, their intended use and daily dosage. HPLC analysis of FA content in 30 randomly purchased supplements exposed that in four of the tested products, FA content was less than 4% of the declared value (DV). Another 11 samples exposed that the difference with declared FA content varied from 25% up to 80% of the DV. The obtained results are in agreement with the ones from inspections previously conducted on the Polish dietary supplements market and indicate the urgent need to implement improvements in the notification system as well as the monitorization of these product’s authenticity. |
format | Online Article Text |
id | pubmed-9460679 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94606792022-09-10 Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market Czarnowska-Kujawska, Marta Klepacka, Joanna Zielińska, Olga Samaniego-Vaesken, María de Lourdes Nutrients Article One way of increasing folate status, especially in a state of increased demand (e.g., women of childbearing age), is dietary supplementation with folic acid (FA). The dietary supplements market in Poland shows a controversial situation and, for many reasons (the ease of placing them on the market, the lack of control of chemical composition), the possibility of inaccurate information provided on the supplement’s label arises. We questioned whether FA supplements available in Poland are indeed complying with regulations and if they could actually improve folate status amongst the target population groups consuming them. Almost 500 products containing FA were identified and available for sale in pharmacies, all of them including specific information provided by manufacturers on the packaging, such as the amount of FA, their intended use and daily dosage. HPLC analysis of FA content in 30 randomly purchased supplements exposed that in four of the tested products, FA content was less than 4% of the declared value (DV). Another 11 samples exposed that the difference with declared FA content varied from 25% up to 80% of the DV. The obtained results are in agreement with the ones from inspections previously conducted on the Polish dietary supplements market and indicate the urgent need to implement improvements in the notification system as well as the monitorization of these product’s authenticity. MDPI 2022-08-25 /pmc/articles/PMC9460679/ /pubmed/36079757 http://dx.doi.org/10.3390/nu14173500 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Czarnowska-Kujawska, Marta Klepacka, Joanna Zielińska, Olga Samaniego-Vaesken, María de Lourdes Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market |
title | Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market |
title_full | Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market |
title_fullStr | Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market |
title_full_unstemmed | Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market |
title_short | Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market |
title_sort | characteristics of dietary supplements with folic acid available on the polish market |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460679/ https://www.ncbi.nlm.nih.gov/pubmed/36079757 http://dx.doi.org/10.3390/nu14173500 |
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