Cargando…

Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market

One way of increasing folate status, especially in a state of increased demand (e.g., women of childbearing age), is dietary supplementation with folic acid (FA). The dietary supplements market in Poland shows a controversial situation and, for many reasons (the ease of placing them on the market, t...

Descripción completa

Detalles Bibliográficos
Autores principales: Czarnowska-Kujawska, Marta, Klepacka, Joanna, Zielińska, Olga, Samaniego-Vaesken, María de Lourdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460679/
https://www.ncbi.nlm.nih.gov/pubmed/36079757
http://dx.doi.org/10.3390/nu14173500
_version_ 1784786806259056640
author Czarnowska-Kujawska, Marta
Klepacka, Joanna
Zielińska, Olga
Samaniego-Vaesken, María de Lourdes
author_facet Czarnowska-Kujawska, Marta
Klepacka, Joanna
Zielińska, Olga
Samaniego-Vaesken, María de Lourdes
author_sort Czarnowska-Kujawska, Marta
collection PubMed
description One way of increasing folate status, especially in a state of increased demand (e.g., women of childbearing age), is dietary supplementation with folic acid (FA). The dietary supplements market in Poland shows a controversial situation and, for many reasons (the ease of placing them on the market, the lack of control of chemical composition), the possibility of inaccurate information provided on the supplement’s label arises. We questioned whether FA supplements available in Poland are indeed complying with regulations and if they could actually improve folate status amongst the target population groups consuming them. Almost 500 products containing FA were identified and available for sale in pharmacies, all of them including specific information provided by manufacturers on the packaging, such as the amount of FA, their intended use and daily dosage. HPLC analysis of FA content in 30 randomly purchased supplements exposed that in four of the tested products, FA content was less than 4% of the declared value (DV). Another 11 samples exposed that the difference with declared FA content varied from 25% up to 80% of the DV. The obtained results are in agreement with the ones from inspections previously conducted on the Polish dietary supplements market and indicate the urgent need to implement improvements in the notification system as well as the monitorization of these product’s authenticity.
format Online
Article
Text
id pubmed-9460679
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94606792022-09-10 Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market Czarnowska-Kujawska, Marta Klepacka, Joanna Zielińska, Olga Samaniego-Vaesken, María de Lourdes Nutrients Article One way of increasing folate status, especially in a state of increased demand (e.g., women of childbearing age), is dietary supplementation with folic acid (FA). The dietary supplements market in Poland shows a controversial situation and, for many reasons (the ease of placing them on the market, the lack of control of chemical composition), the possibility of inaccurate information provided on the supplement’s label arises. We questioned whether FA supplements available in Poland are indeed complying with regulations and if they could actually improve folate status amongst the target population groups consuming them. Almost 500 products containing FA were identified and available for sale in pharmacies, all of them including specific information provided by manufacturers on the packaging, such as the amount of FA, their intended use and daily dosage. HPLC analysis of FA content in 30 randomly purchased supplements exposed that in four of the tested products, FA content was less than 4% of the declared value (DV). Another 11 samples exposed that the difference with declared FA content varied from 25% up to 80% of the DV. The obtained results are in agreement with the ones from inspections previously conducted on the Polish dietary supplements market and indicate the urgent need to implement improvements in the notification system as well as the monitorization of these product’s authenticity. MDPI 2022-08-25 /pmc/articles/PMC9460679/ /pubmed/36079757 http://dx.doi.org/10.3390/nu14173500 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Czarnowska-Kujawska, Marta
Klepacka, Joanna
Zielińska, Olga
Samaniego-Vaesken, María de Lourdes
Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market
title Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market
title_full Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market
title_fullStr Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market
title_full_unstemmed Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market
title_short Characteristics of Dietary Supplements with Folic Acid Available on the Polish Market
title_sort characteristics of dietary supplements with folic acid available on the polish market
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460679/
https://www.ncbi.nlm.nih.gov/pubmed/36079757
http://dx.doi.org/10.3390/nu14173500
work_keys_str_mv AT czarnowskakujawskamarta characteristicsofdietarysupplementswithfolicacidavailableonthepolishmarket
AT klepackajoanna characteristicsofdietarysupplementswithfolicacidavailableonthepolishmarket
AT zielinskaolga characteristicsofdietarysupplementswithfolicacidavailableonthepolishmarket
AT samaniegovaeskenmariadelourdes characteristicsofdietarysupplementswithfolicacidavailableonthepolishmarket