Therapeutic efficacy of human adipose mesenchymal stem cells in Crohn’s colon fibrosis is improved by IFN-γ and kynurenic acid priming through indoleamine 2,3-dioxygenase-1 signaling

BACKGROUND: Inflammatory bowel diseases (IBD) are chronic relapsing–remitting inflammatory diseases of the gastrointestinal tract that are typically categorized into two subtypes: Crohn's disease (CD) and ulcerative colitis (UC). Although MSCs therapy has achieved encouraging outcomes in IBD th...

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Detalles Bibliográficos
Autores principales: Ye, Yixin, Zhang, Xiaomei, Su, Dongsheng, Ren, Yushuang, Cheng, Fuyi, Yao, Yunqi, Shi, Gang, Ji, Yanhong, Chen, Shuang, Shi, Pengyi, Dai, Lei, Su, Xiaolan, Deng, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461110/
https://www.ncbi.nlm.nih.gov/pubmed/36076306
http://dx.doi.org/10.1186/s13287-022-03157-8

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