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ROS attenuates TET2-dependent ZO-1 epigenetic expression in cerebral vascular endothelial cells

AIMS: To investigate whether DNA active demethylase TET regulates the expression of tight junction proteins in endothelial cells of the blood–brain barrier (BBB). METHODS: Correlations between TET2 activity (indicated by its catalytic product 5hmC) and the expression of BBB tight junction proteins w...

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Detalles Bibliográficos
Autores principales:	Wang, Lan, Mao, Bei, Fan, Keyang, Sun, Renqiang, Zhang, Jialong, Liang, Huazheng, Liu, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461112/ https://www.ncbi.nlm.nih.gov/pubmed/36076297 http://dx.doi.org/10.1186/s12987-022-00370-8

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