Small and long RNA transcriptome of whole human cerebrospinal fluid and serum as compared to their extracellular vesicle fractions reveal profound differences in expression patterns and impacts on biological processes

BACKGROUND: Next generation sequencing (NGS) of human specimen is expected to improve prognosis and diagnosis of human diseases, but its sensitivity urges for well-defined sampling and standardized protocols in order to avoid error-prone conclusions. METHODS: In this study, large volumes of pooled h...

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Detalles Bibliográficos
Autores principales: Michel, Uwe, Shomroni, Orr, Müller, Barbara, Lange, Peter, Salinas, Gabriela, Bähr, Mathias, Koch, Jan Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461220/
https://www.ncbi.nlm.nih.gov/pubmed/36076207
http://dx.doi.org/10.1186/s12967-022-03612-3

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