Characterization of passive permeability after low intensity focused ultrasound mediated blood–brain barrier disruption in a preclinical model

BACKGROUND: Systemic drug delivery to the central nervous system is limited by presence of the blood–brain barrier (BBB). Low intensity focused ultrasound (LiFUS) is a non-invasive technique to disrupt the BBB, though there is a lack of understanding of the relationship between LiFUS parameters, suc...

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Detalles Bibliográficos
Autores principales: Arsiwala, Tasneem A., Sprowls, Samuel A., Blethen, Kathryn E., Fladeland, Ross A., Wolford, Cullen P., Kielkowski, Brooke N., Glass, Morgan J., Wang, Peng, Wilson, Olivia, Carpenter, Jeffrey S., Ranjan, Manish, Finomore, Victor, Rezai, Ali, Lockman, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461249/
https://www.ncbi.nlm.nih.gov/pubmed/36076213
http://dx.doi.org/10.1186/s12987-022-00369-1

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