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AANG Prevents Smad3-dependent Diabetic Nephropathy by Restoring Pancreatic β-Cell Development in db/db Mice
Diabetic nephropathy (DN) is a major cause of end-stage kidney disease, where TGF-β1/Smad signaling plays an important role in the disease progression. Our previous studies demonstrated a combination of Traditional Chinese Medicine derived Smad7 agonist Asiatic Acid (AA) and Smad3 inhibitor Naringen...
Autores principales: | Chung, Jeff Yat-Fai, Tang, Patrick Ming-Kuen, Chan, Max Kam-Kwan, Wang, Li, Huang, Xiao-Ru, To, Ka-Fai, Ma, Ronald CW, Lan, Hui-Yao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461652/ https://www.ncbi.nlm.nih.gov/pubmed/36147472 http://dx.doi.org/10.7150/ijbs.72977 |
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