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Csf1r mediates enhancement of intestinal tumorigenesis caused by inactivation of Mir34a

The CSF1 receptor (CSF1R) encoding mRNA represents a direct target of miR-34a. However, the in vivo relevance of the suppression of CSF1R by miR-34a for intestinal tumor suppression mediated by the p53/miR-34a pathway has remained unknown. Here, Apc(Min/+) mice with intestinal-epithelial cell (IEC)-...

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Detalles Bibliográficos
Autores principales:	Liu, Fangteng, Bouznad, Nassim, Kaller, Markus, Shi, Xiaolong, König, Janine, Jaeckel, Stephanie, Hermeking, Heiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461672/ https://www.ncbi.nlm.nih.gov/pubmed/36147476 http://dx.doi.org/10.7150/ijbs.75503

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