Cargando…

The ECRG4 cleavage product augurin binds the endotoxin receptor and influences the innate immune response during otitis media

Otitis media (OM), the most common disease of childhood, is typically characterized by bacterial infection of the middle ear (ME). Prominent features of OM include hyperplasia of the ME mucosa, which transforms from a monolayer of simple squamous epithelium with minimal stroma into a full-thickness...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kurabi, Arwa, Hur, Dong Gu, Pak, Kwang, Gibson, Madeline, Webster, Nicholas J. G., Baird, Andrew, Eliceiri, Brian P., Ryan, Allen F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461705/ https://www.ncbi.nlm.nih.gov/pubmed/36092940 http://dx.doi.org/10.3389/fgene.2022.932555

Ejemplares similares

Ecrg4 Attenuates the Inflammatory Proliferative Response of Mucosal Epithelial Cells to Infection
por: Kurabi, Arwa, et al.
Publicado: (2013)

Essential Role of the Innate Immune Adaptor RIP2 in the Response to Otitis Media
por: Kurabi, Arwa, et al.
Publicado: (2022)

Ecrg4 expression and its product augurin in the choroid plexus: impact on fetal brain development, cerebrospinal fluid homeostasis and neuroprogenitor cell response to CNS injury
por: Gonzalez, Ana Maria, et al.
Publicado: (2011)

Leukotriene B4 Is a Major Determinant of Leukocyte Recruitment During Otitis Media
por: Heo, Kyung Wook, et al.
Publicado: (2021)

Augurin production in the mammalian choroid plexus: Implications for CSF and hydrocephalus
por: Podvin, Sonia, et al.
Publicado: (2010)

Lack of the hyaluronan receptor CD44 affects the course of bacterial otitis media and reduces leukocyte recruitment to the middle ear
por: Lim, Hyun Woo, et al.
Publicado: (2019)

Resolution of otitis media in a humanized mouse model
por: Son, Ye Lin, et al.
Publicado: (2022)

NOD1/NOD2-mediated recognition of non-typeable Haemophilus influenzae activates innate immunity during otitis media
por: Lee, Jasmine, et al.
Publicado: (2019)

A Mouse Model of Otitis Media Identifies HB-EGF as a Mediator of Inflammation-Induced Mucosal Proliferation
por: Suzukawa, Keigo, et al.
Publicado: (2014)

HB-EGF Plays a Pivotal Role in Mucosal Hyperplasia During Otitis Media Induced by a Viral Analog
por: Sakamoto, Takashi, et al.
Publicado: (2022)

A kinase inhibitor screen identifies signaling pathways regulating mucosal growth during otitis media
por: Noel, Julia, et al.
Publicado: (2020)

ECRG-4 expression in normal and neoplastic choroid plexus
por: Donahue, John E, et al.
Publicado: (2010)

Immunomodulation as a Protective Strategy in Chronic Otitis Media
por: Leichtle, Anke, et al.
Publicado: (2022)

ECRG4 regulates neutrophil recruitment and CD44 expression during the inflammatory response to injury
por: Dorschner, Robert A., et al.
Publicado: (2020)

The transcriptome of a complete episode of acute otitis media
por: Hernandez, Michelle, et al.
Publicado: (2015)

Complex and pleiotropic signaling pathways regulated by the secreted protein augurin
por: Richter, Margaux, et al.
Publicado: (2023)

Innate Signaling in Otitis Media: Pathogenesis and Recovery
por: Leichtle, Anke, et al.
Publicado: (2010)

The Toll-Like receptor adaptor TRIF contributes to otitis media pathogenesis and recovery
por: Leichtle, Anke, et al.
Publicado: (2009)

Discovery of a Biological Mechanism of Active Transport through the Tympanic Membrane to the Middle Ear
por: Kurabi, Arwa, et al.
Publicado: (2016)

Surfactant proteins and innate immunity of otitis media
por: Abdel-Razek, Osama, et al.
Publicado: (2022)

C-Jun N-terminal kinase (JNK) isoforms play differing roles in otitis media
por: Yao, William, et al.
Publicado: (2014)

Hearing rehabilitation and microbial shift after middle ear surgery with Vibrant Soundbridge in patients with chronic otitis media
por: Bruchhage, Karl-Ludwig, et al.
Publicado: (2023)

Screening Mammalian Cochlear Hair Cells to Identify Critical Processes in Aminoglycoside-Mediated Damage
por: Lim, Hyun Woo, et al.
Publicado: (2018)

Innate immunity of surfactant protein A in experimental otitis media
por: Abdel-Razek, Osama, et al.
Publicado: (2019)

The Roles of NOD-like Receptors in Innate Immunity in Otitis Media
por: You, Myung-Won, et al.
Publicado: (2022)

Ecrg4 peptide is the ligand of multiple scavenger receptors
por: Moriguchi, Tetsuo, et al.
Publicado: (2018)

Downregulation and DNA methylation of ECRG4 in gastric cancer
por: Deng, Peng, et al.
Publicado: (2018)

Loss of Ecrg4 improves calcium oxalate nephropathy
por: Cabuzu, Daniela, et al.
Publicado: (2022)

A kinase inhibitor library screen identifies novel enzymes involved in ototoxic damage to the murine organ of Corti
por: Ryals, Matthew, et al.
Publicado: (2017)

An Antioxidant Screen Identifies Candidates for Protection of Cochlear Hair Cells from Gentamicin Toxicity
por: Noack, Volker, et al.
Publicado: (2017)

A transcytotic transport mechanism across the tympanic membrane
por: Kurabi, Arwa, et al.
Publicado: (2022)

Single-Cell Transcriptomes Reveal a Complex Cellular Landscape in the Middle Ear and Differential Capacities for Acute Response to Infection
por: Ryan, Allen F., et al.
Publicado: (2020)

Otitis Externa, Otitis Media, and Mastoiditis
por: Klein, Jerome O.
Publicado: (2015)

A novel tumor suppressor gene ECRG4 interacts directly with TMPRSS11A (ECRG1) to inhibit cancer cell growth in esophageal carcinoma
por: Li, Lin-wei, et al.
Publicado: (2011)

Screening antioxidants for the protection of cochlear sensory cells
por: Hur, Dong Gu, et al.
Publicado: (2018)

Otitis Media
por: Gotcsik, Marah
Publicado: (2012)

Otitis media
por: Schilder, Anne G. M., et al.
Publicado: (2016)

Otitis Media
por: Schauer, Lora L.
Publicado: (2007)

Immunohistochemical and qPCR Detection of SARS-CoV-2 in the Human Middle Ear Versus the Nasal Cavity: Case Series
por: Kurabi, Arwa, et al.
Publicado: (2021)

TNFA deletion alters apoptosis as well as caspase 3 and 4 expression during otitis media
por: Ebmeyer, Joerg, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_mpf7i249pddoeddeokp7kal0fu