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Bis{[amino(iminiumyl)methyl]urea} tetrakis{2-[(dimethylamino)(iminiumyl)methyl]guanidine} di-μ(6)-oxido-tetra-μ(3)-oxido-tetradeca-μ(2)-oxido-octaoxidodecavanadium(V) tetrahydrate
The title compound, (C(4)H(12)N(5))(4)(C(2)H(7)N(4)O)(2)[V(10)O(28)]·4H(2)O, is a by-product obtained by reacting ammonium metavanadate(V), metformin hydrochloride and acetic acid in the presence of sodium hypochlorite, at pH = 5. The crystal structure comprises a decavanadate(V) anion (V(10)O(28)...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462036/ https://www.ncbi.nlm.nih.gov/pubmed/36339897 http://dx.doi.org/10.1107/S2414314622006277 |
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author | Pérez-Benítez, Aarón Ariza-Ramírez, Jorge Luis Fortis-Valera, Monserrat Arroyo-Carmona, Rosa Elena Martínez de la Luz, María Isabel Ramírez-Contreras, Diego Bernès, Sylvain |
author_facet | Pérez-Benítez, Aarón Ariza-Ramírez, Jorge Luis Fortis-Valera, Monserrat Arroyo-Carmona, Rosa Elena Martínez de la Luz, María Isabel Ramírez-Contreras, Diego Bernès, Sylvain |
author_sort | Pérez-Benítez, Aarón |
collection | PubMed |
description | The title compound, (C(4)H(12)N(5))(4)(C(2)H(7)N(4)O)(2)[V(10)O(28)]·4H(2)O, is a by-product obtained by reacting ammonium metavanadate(V), metformin hydrochloride and acetic acid in the presence of sodium hypochlorite, at pH = 5. The crystal structure comprises a decavanadate(V) anion (V(10)O(28))(6–) lying on an inversion centre in space group P [Image: see text] , while cations and solvent water molecules are placed in general positions, surrounding the anion, and forming numerous N—H⋯O and O—H⋯O hydrogen bonds. Metforminium (C(4)H(12)N(5))(+) and guanylurea (C(2)H(7)N(4)O)(+) cations display the expected shape. Interestingly, in physiology the latter cation is known to be the main metabolite of the former one. The reported structure thus supports the role of sodium hypochlorite as an oxidizing reagent being able to degrade metformin hydrochloride to form guanylurea. [Image: see text] |
format | Online Article Text |
id | pubmed-9462036 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-94620362022-11-04 Bis{[amino(iminiumyl)methyl]urea} tetrakis{2-[(dimethylamino)(iminiumyl)methyl]guanidine} di-μ(6)-oxido-tetra-μ(3)-oxido-tetradeca-μ(2)-oxido-octaoxidodecavanadium(V) tetrahydrate Pérez-Benítez, Aarón Ariza-Ramírez, Jorge Luis Fortis-Valera, Monserrat Arroyo-Carmona, Rosa Elena Martínez de la Luz, María Isabel Ramírez-Contreras, Diego Bernès, Sylvain IUCrdata Data Reports The title compound, (C(4)H(12)N(5))(4)(C(2)H(7)N(4)O)(2)[V(10)O(28)]·4H(2)O, is a by-product obtained by reacting ammonium metavanadate(V), metformin hydrochloride and acetic acid in the presence of sodium hypochlorite, at pH = 5. The crystal structure comprises a decavanadate(V) anion (V(10)O(28))(6–) lying on an inversion centre in space group P [Image: see text] , while cations and solvent water molecules are placed in general positions, surrounding the anion, and forming numerous N—H⋯O and O—H⋯O hydrogen bonds. Metforminium (C(4)H(12)N(5))(+) and guanylurea (C(2)H(7)N(4)O)(+) cations display the expected shape. Interestingly, in physiology the latter cation is known to be the main metabolite of the former one. The reported structure thus supports the role of sodium hypochlorite as an oxidizing reagent being able to degrade metformin hydrochloride to form guanylurea. [Image: see text] International Union of Crystallography 2022-06-24 /pmc/articles/PMC9462036/ /pubmed/36339897 http://dx.doi.org/10.1107/S2414314622006277 Text en © Pérez-Benítez et al. 2022 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Data Reports Pérez-Benítez, Aarón Ariza-Ramírez, Jorge Luis Fortis-Valera, Monserrat Arroyo-Carmona, Rosa Elena Martínez de la Luz, María Isabel Ramírez-Contreras, Diego Bernès, Sylvain Bis{[amino(iminiumyl)methyl]urea} tetrakis{2-[(dimethylamino)(iminiumyl)methyl]guanidine} di-μ(6)-oxido-tetra-μ(3)-oxido-tetradeca-μ(2)-oxido-octaoxidodecavanadium(V) tetrahydrate |
title | Bis{[amino(iminiumyl)methyl]urea} tetrakis{2-[(dimethylamino)(iminiumyl)methyl]guanidine} di-μ(6)-oxido-tetra-μ(3)-oxido-tetradeca-μ(2)-oxido-octaoxidodecavanadium(V) tetrahydrate |
title_full | Bis{[amino(iminiumyl)methyl]urea} tetrakis{2-[(dimethylamino)(iminiumyl)methyl]guanidine} di-μ(6)-oxido-tetra-μ(3)-oxido-tetradeca-μ(2)-oxido-octaoxidodecavanadium(V) tetrahydrate |
title_fullStr | Bis{[amino(iminiumyl)methyl]urea} tetrakis{2-[(dimethylamino)(iminiumyl)methyl]guanidine} di-μ(6)-oxido-tetra-μ(3)-oxido-tetradeca-μ(2)-oxido-octaoxidodecavanadium(V) tetrahydrate |
title_full_unstemmed | Bis{[amino(iminiumyl)methyl]urea} tetrakis{2-[(dimethylamino)(iminiumyl)methyl]guanidine} di-μ(6)-oxido-tetra-μ(3)-oxido-tetradeca-μ(2)-oxido-octaoxidodecavanadium(V) tetrahydrate |
title_short | Bis{[amino(iminiumyl)methyl]urea} tetrakis{2-[(dimethylamino)(iminiumyl)methyl]guanidine} di-μ(6)-oxido-tetra-μ(3)-oxido-tetradeca-μ(2)-oxido-octaoxidodecavanadium(V) tetrahydrate |
title_sort | bis{[amino(iminiumyl)methyl]urea} tetrakis{2-[(dimethylamino)(iminiumyl)methyl]guanidine} di-μ(6)-oxido-tetra-μ(3)-oxido-tetradeca-μ(2)-oxido-octaoxidodecavanadium(v) tetrahydrate |
topic | Data Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462036/ https://www.ncbi.nlm.nih.gov/pubmed/36339897 http://dx.doi.org/10.1107/S2414314622006277 |
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