Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury

BACKGROUND: Acute kidney injury (AKI) occurs frequently in critically ill patients and is associated with adverse outcomes. Cellular mechanisms underlying AKI and kidney cell responses to injury remain incompletely understood. METHODS: We performed single-nuclei transcriptomics, bulk transcriptomics...

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Detalles Bibliográficos
Autores principales: Hinze, Christian, Kocks, Christine, Leiz, Janna, Karaiskos, Nikos, Boltengagen, Anastasiya, Cao, Shuang, Skopnik, Christopher Mark, Klocke, Jan, Hardenberg, Jan-Hendrik, Stockmann, Helena, Gotthardt, Inka, Obermayer, Benedikt, Haghverdi, Laleh, Wyler, Emanuel, Landthaler, Markus, Bachmann, Sebastian, Hocke, Andreas C., Corman, Victor, Busch, Jonas, Schneider, Wolfgang, Himmerkus, Nina, Bleich, Markus, Eckardt, Kai-Uwe, Enghard, Philipp, Rajewsky, Nikolaus, Schmidt-Ott, Kai M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462075/
https://www.ncbi.nlm.nih.gov/pubmed/36085050
http://dx.doi.org/10.1186/s13073-022-01108-9

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