(3S,5R,6S)-Di­phenyl­methyl 1-oxo-6-bromo­penicillanate

In the title compound, C(21)H(20)BrNO(4)S, a key inter­mediate in the synthesis of the widely used β-lactamase inhibitor tazobactam, the five-membered thia­zolidine ring adopts an envelope conformation and the four-membered azetidine ring is in a distorted planar conformation. The crystal structure...

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Detalles Bibliográficos
Autores principales: Soundararajan, Krishnan, Sethuraman, Velusamy, Thanigaimani, Kaliyaperumal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Data Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462188/
https://www.ncbi.nlm.nih.gov/pubmed/36340841
http://dx.doi.org/10.1107/S2414314620001431
Descripción
Sumario:In the title compound, C(21)H(20)BrNO(4)S, a key inter­mediate in the synthesis of the widely used β-lactamase inhibitor tazobactam, the five-membered thia­zolidine ring adopts an envelope conformation and the four-membered azetidine ring is in a distorted planar conformation. The crystal structure features C—H⋯O hydrogen bonds and a weak C—H⋯π inter­action. [Image: see text]

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