Cargando…

Ethyl 10α-hy­droxy-4,9-dimethyl-14-oxo-3,8,15-trioxa­tetra­cyclo­[10.3.0.0(2,4).0(7,9)]penta­decane-13-spiro-5′-pyrazole-3′-carboxyl­ate

The ten-membered ring in the title mol­ecule, C(25)H(29)ClN(2)O(7), adopts an approximate chair–chair conformation, whereas the five-membered furan and pyrazole rings display envelope conformations. The mean plane of the furan ring is almost perpendicular to that of the pyrazole ring, as indicated b...

Descripción completa

Detalles Bibliográficos
Autores principales: Outahar, Fatima, Moumou, Mohamed, Rakib, El Mostapha, Hannioui, Abdellah, Saadi, Mohamed, El Ammari, Lahcen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462250/
https://www.ncbi.nlm.nih.gov/pubmed/36339783
http://dx.doi.org/10.1107/S2414314620009451
Descripción
Sumario:The ten-membered ring in the title mol­ecule, C(25)H(29)ClN(2)O(7), adopts an approximate chair–chair conformation, whereas the five-membered furan and pyrazole rings display envelope conformations. The mean plane of the furan ring is almost perpendicular to that of the pyrazole ring, as indicated by the dihedral angle between them of 86.45 (9)°. The pyrazole ring is slightly inclined to the plane of the attached phenyl ring, subtending a dihedral angle of 16.88 (8)°. The conformation of the mol­ecule is stabilized by six intra­molecular hydrogen bonds and crystal cohesion is ensured by five C—H⋯O hydrogen bonds, in addition to C—H⋯π inter­actions. [Image: see text]