Ethyl 10α-hy­droxy-4,9-dimethyl-14-oxo-3,8,15-trioxa­tetra­cyclo­[10.3.0.0(2,4).0(7,9)]penta­decane-13-spiro-5′-pyrazole-3′-carboxyl­ate

The ten-membered ring in the title mol­ecule, C(25)H(29)ClN(2)O(7), adopts an approximate chair–chair conformation, whereas the five-membered furan and pyrazole rings display envelope conformations. The mean plane of the furan ring is almost perpendicular to that of the pyrazole ring, as indicated b...

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Autores principales: Outahar, Fatima, Moumou, Mohamed, Rakib, El Mostapha, Hannioui, Abdellah, Saadi, Mohamed, El Ammari, Lahcen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Data Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462250/
https://www.ncbi.nlm.nih.gov/pubmed/36339783
http://dx.doi.org/10.1107/S2414314620009451
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author Outahar, Fatima
Moumou, Mohamed
Rakib, El Mostapha
Hannioui, Abdellah
Saadi, Mohamed
El Ammari, Lahcen
author_facet Outahar, Fatima
Moumou, Mohamed
Rakib, El Mostapha
Hannioui, Abdellah
Saadi, Mohamed
El Ammari, Lahcen
author_sort Outahar, Fatima
collection PubMed
description The ten-membered ring in the title mol­ecule, C(25)H(29)ClN(2)O(7), adopts an approximate chair–chair conformation, whereas the five-membered furan and pyrazole rings display envelope conformations. The mean plane of the furan ring is almost perpendicular to that of the pyrazole ring, as indicated by the dihedral angle between them of 86.45 (9)°. The pyrazole ring is slightly inclined to the plane of the attached phenyl ring, subtending a dihedral angle of 16.88 (8)°. The conformation of the mol­ecule is stabilized by six intra­molecular hydrogen bonds and crystal cohesion is ensured by five C—H⋯O hydrogen bonds, in addition to C—H⋯π inter­actions. [Image: see text]
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spelling pubmed-94622502022-11-04 Ethyl 10α-hy­droxy-4,9-dimethyl-14-oxo-3,8,15-trioxa­tetra­cyclo­[10.3.0.0(2,4).0(7,9)]penta­decane-13-spiro-5′-pyrazole-3′-carboxyl­ate Outahar, Fatima Moumou, Mohamed Rakib, El Mostapha Hannioui, Abdellah Saadi, Mohamed El Ammari, Lahcen IUCrdata Data Reports The ten-membered ring in the title mol­ecule, C(25)H(29)ClN(2)O(7), adopts an approximate chair–chair conformation, whereas the five-membered furan and pyrazole rings display envelope conformations. The mean plane of the furan ring is almost perpendicular to that of the pyrazole ring, as indicated by the dihedral angle between them of 86.45 (9)°. The pyrazole ring is slightly inclined to the plane of the attached phenyl ring, subtending a dihedral angle of 16.88 (8)°. The conformation of the mol­ecule is stabilized by six intra­molecular hydrogen bonds and crystal cohesion is ensured by five C—H⋯O hydrogen bonds, in addition to C—H⋯π inter­actions. [Image: see text] International Union of Crystallography 2020-07-21 /pmc/articles/PMC9462250/ /pubmed/36339783 http://dx.doi.org/10.1107/S2414314620009451 Text en © Outahar et al. 2020 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Data Reports
Outahar, Fatima
Moumou, Mohamed
Rakib, El Mostapha
Hannioui, Abdellah
Saadi, Mohamed
El Ammari, Lahcen
Ethyl 10α-hy­droxy-4,9-dimethyl-14-oxo-3,8,15-trioxa­tetra­cyclo­[10.3.0.0(2,4).0(7,9)]penta­decane-13-spiro-5′-pyrazole-3′-carboxyl­ate
title Ethyl 10α-hy­droxy-4,9-dimethyl-14-oxo-3,8,15-trioxa­tetra­cyclo­[10.3.0.0(2,4).0(7,9)]penta­decane-13-spiro-5′-pyrazole-3′-carboxyl­ate
title_full Ethyl 10α-hy­droxy-4,9-dimethyl-14-oxo-3,8,15-trioxa­tetra­cyclo­[10.3.0.0(2,4).0(7,9)]penta­decane-13-spiro-5′-pyrazole-3′-carboxyl­ate
title_fullStr Ethyl 10α-hy­droxy-4,9-dimethyl-14-oxo-3,8,15-trioxa­tetra­cyclo­[10.3.0.0(2,4).0(7,9)]penta­decane-13-spiro-5′-pyrazole-3′-carboxyl­ate
title_full_unstemmed Ethyl 10α-hy­droxy-4,9-dimethyl-14-oxo-3,8,15-trioxa­tetra­cyclo­[10.3.0.0(2,4).0(7,9)]penta­decane-13-spiro-5′-pyrazole-3′-carboxyl­ate
title_short Ethyl 10α-hy­droxy-4,9-dimethyl-14-oxo-3,8,15-trioxa­tetra­cyclo­[10.3.0.0(2,4).0(7,9)]penta­decane-13-spiro-5′-pyrazole-3′-carboxyl­ate
title_sort ethyl 10α-hy­droxy-4,9-dimethyl-14-oxo-3,8,15-trioxa­tetra­cyclo­[10.3.0.0(2,4).0(7,9)]penta­decane-13-spiro-5′-pyrazole-3′-carboxyl­ate
topic Data Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462250/
https://www.ncbi.nlm.nih.gov/pubmed/36339783
http://dx.doi.org/10.1107/S2414314620009451
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