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1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(meth­yl)amino]­piperidin-1-yl}propan-1-one

The title compound, C(19)H(22)FN(5)O, has been synthesized as an inhibitor of glycogen synthase kinase-3β. Two mol­ecules inter­act via two N—H⋯N hydrogen bonds, forming centrosymmetric dimers. [Image: see text]

Detalles Bibliográficos
Autores principales: Andreev, Stanislav, Schollmeyer, Dieter, Koch, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462319/
https://www.ncbi.nlm.nih.gov/pubmed/36338864
http://dx.doi.org/10.1107/S2414314621001590
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author Andreev, Stanislav
Schollmeyer, Dieter
Koch, Pierre
author_facet Andreev, Stanislav
Schollmeyer, Dieter
Koch, Pierre
author_sort Andreev, Stanislav
collection PubMed
description The title compound, C(19)H(22)FN(5)O, has been synthesized as an inhibitor of glycogen synthase kinase-3β. Two mol­ecules inter­act via two N—H⋯N hydrogen bonds, forming centrosymmetric dimers. [Image: see text]
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spelling pubmed-94623192022-11-04 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(meth­yl)amino]­piperidin-1-yl}propan-1-one Andreev, Stanislav Schollmeyer, Dieter Koch, Pierre IUCrdata Data Reports The title compound, C(19)H(22)FN(5)O, has been synthesized as an inhibitor of glycogen synthase kinase-3β. Two mol­ecules inter­act via two N—H⋯N hydrogen bonds, forming centrosymmetric dimers. [Image: see text] International Union of Crystallography 2021-02-23 /pmc/articles/PMC9462319/ /pubmed/36338864 http://dx.doi.org/10.1107/S2414314621001590 Text en © Andreev et al. 2021 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Data Reports
Andreev, Stanislav
Schollmeyer, Dieter
Koch, Pierre
1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(meth­yl)amino]­piperidin-1-yl}propan-1-one
title 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(meth­yl)amino]­piperidin-1-yl}propan-1-one
title_full 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(meth­yl)amino]­piperidin-1-yl}propan-1-one
title_fullStr 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(meth­yl)amino]­piperidin-1-yl}propan-1-one
title_full_unstemmed 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(meth­yl)amino]­piperidin-1-yl}propan-1-one
title_short 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(meth­yl)amino]­piperidin-1-yl}propan-1-one
title_sort 1-{3-[(7-fluoro-9h-pyrimido[4,5-b]indol-4-yl)(meth­yl)amino]­piperidin-1-yl}propan-1-one
topic Data Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462319/
https://www.ncbi.nlm.nih.gov/pubmed/36338864
http://dx.doi.org/10.1107/S2414314621001590
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