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1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(methyl)amino]piperidin-1-yl}propan-1-one
The title compound, C(19)H(22)FN(5)O, has been synthesized as an inhibitor of glycogen synthase kinase-3β. Two molecules interact via two N—H⋯N hydrogen bonds, forming centrosymmetric dimers. [Image: see text]
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462319/ https://www.ncbi.nlm.nih.gov/pubmed/36338864 http://dx.doi.org/10.1107/S2414314621001590 |
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author | Andreev, Stanislav Schollmeyer, Dieter Koch, Pierre |
author_facet | Andreev, Stanislav Schollmeyer, Dieter Koch, Pierre |
author_sort | Andreev, Stanislav |
collection | PubMed |
description | The title compound, C(19)H(22)FN(5)O, has been synthesized as an inhibitor of glycogen synthase kinase-3β. Two molecules interact via two N—H⋯N hydrogen bonds, forming centrosymmetric dimers. [Image: see text] |
format | Online Article Text |
id | pubmed-9462319 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-94623192022-11-04 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(methyl)amino]piperidin-1-yl}propan-1-one Andreev, Stanislav Schollmeyer, Dieter Koch, Pierre IUCrdata Data Reports The title compound, C(19)H(22)FN(5)O, has been synthesized as an inhibitor of glycogen synthase kinase-3β. Two molecules interact via two N—H⋯N hydrogen bonds, forming centrosymmetric dimers. [Image: see text] International Union of Crystallography 2021-02-23 /pmc/articles/PMC9462319/ /pubmed/36338864 http://dx.doi.org/10.1107/S2414314621001590 Text en © Andreev et al. 2021 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Data Reports Andreev, Stanislav Schollmeyer, Dieter Koch, Pierre 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(methyl)amino]piperidin-1-yl}propan-1-one |
title | 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(methyl)amino]piperidin-1-yl}propan-1-one |
title_full | 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(methyl)amino]piperidin-1-yl}propan-1-one |
title_fullStr | 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(methyl)amino]piperidin-1-yl}propan-1-one |
title_full_unstemmed | 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(methyl)amino]piperidin-1-yl}propan-1-one |
title_short | 1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(methyl)amino]piperidin-1-yl}propan-1-one |
title_sort | 1-{3-[(7-fluoro-9h-pyrimido[4,5-b]indol-4-yl)(methyl)amino]piperidin-1-yl}propan-1-one |
topic | Data Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462319/ https://www.ncbi.nlm.nih.gov/pubmed/36338864 http://dx.doi.org/10.1107/S2414314621001590 |
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