Enhancing the clinical value of serum neurofilament light chain measurement

BACKGROUND: Serum neurofilament light chain (sNFL) is becoming an important biomarker of neuro-axonal injury. Though sNFL correlates with CSF NFL (cNFL), 40% to 60% of variance remains unexplained. We aimed to mathematically adjust sNFL to strengthen its clinical value. METHODS: We measured NFL in a...

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Detalles Bibliográficos
Autores principales: Kosa, Peter, Masvekar, Ruturaj, Komori, Mika, Phillips, Jonathan, Ramesh, Vighnesh, Varosanec, Mihael, Sandford, Mary, Bielekova, Bibiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462467/
https://www.ncbi.nlm.nih.gov/pubmed/35737460
http://dx.doi.org/10.1172/jci.insight.161415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462467/
https://www.ncbi.nlm.nih.gov/pubmed/35737460
http://dx.doi.org/10.1172/jci.insight.161415

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