Ebola virus protein VP40 stimulates IL-12– and IL-18–dependent activation of human natural killer cells

Accumulation of activated natural killer (NK) cells in tissues during Ebola virus infection contributes to Ebola virus disease (EVD) pathogenesis. Yet, immunization with Ebola virus-like particles (VLPs) comprising glycoprotein and matrix protein VP40 provides rapid, NK cell–mediated protection agai...

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Detalles Bibliográficos
Autores principales: Le, Hung, Spearman, Paul, Waggoner, Stephen N., Singh, Karnail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462474/
https://www.ncbi.nlm.nih.gov/pubmed/35862204
http://dx.doi.org/10.1172/jci.insight.158902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462474/
https://www.ncbi.nlm.nih.gov/pubmed/35862204
http://dx.doi.org/10.1172/jci.insight.158902

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