Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer

Metastatic pancreatic cancer (PDAC) has a poor clinical outcome with a 5-year survival rate below 3%. Recent transcriptome profiling of PDAC biopsies has identified 2 clinically distinct subtypes — the “basal-like” (BL) subtype with poor prognosis and therapy resistance compared with the less aggres...

Descripción completa

Detalles Bibliográficos
Autores principales: Krebs, Niklas, Klein, Lukas, Wegwitz, Florian, Espinet, Elisa, Maurer, Hans Carlo, Tu, Mengyu, Penz, Frederike, Küffer, Stefan, Xu, Xingbo, Bohnenberger, Hanibal, Cameron, Silke, Brunner, Marius, Neesse, Albrecht, Kishore, Uday, Hessmann, Elisabeth, Trumpp, Andreas, Ströbel, Philipp, Brekken, Rolf A., Ellenrieder, Volker, Singh, Shiv K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462476/
https://www.ncbi.nlm.nih.gov/pubmed/35993361
http://dx.doi.org/10.1172/jci.insight.154475

Ejemplares similares

Ejemplares similares