Single-nucleus RNA-Seq reveals singular gene signatures of human ductal cells during adaptation to insulin resistance

Adaptation to increased insulin demand is mediated by β cell proliferation and neogenesis, among other mechanisms. Although it is known that pancreatic β cells can arise from ductal progenitors, these observations have been limited mostly to the neonatal period. We have recently reported that the du...

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Detalles Bibliográficos
Autores principales: Dirice, Ercument, Basile, Giorgio, Kahraman, Sevim, Diegisser, Danielle, Hu, Jiang, Kulkarni, Rohit N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462484/
https://www.ncbi.nlm.nih.gov/pubmed/35819843
http://dx.doi.org/10.1172/jci.insight.153877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462484/
https://www.ncbi.nlm.nih.gov/pubmed/35819843
http://dx.doi.org/10.1172/jci.insight.153877

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