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Single-nucleus RNA-Seq reveals singular gene signatures of human ductal cells during adaptation to insulin resistance
Adaptation to increased insulin demand is mediated by β cell proliferation and neogenesis, among other mechanisms. Although it is known that pancreatic β cells can arise from ductal progenitors, these observations have been limited mostly to the neonatal period. We have recently reported that the du...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462484/ https://www.ncbi.nlm.nih.gov/pubmed/35819843 http://dx.doi.org/10.1172/jci.insight.153877 |