Cargando…
Fetal and maternal NLRP3 signaling is required for preterm labor and birth
Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. One of every 4 preterm neonates is born to a mother with intra-amniotic inflammation driven by invading bacteria. However, the molecular mechanisms underlying this hostile immune response remain unclear. Here, we used...
Autores principales: | Motomura, Kenichiro, Romero, Roberto, Galaz, Jose, Tao, Li, Garcia-Flores, Valeria, Xu, Yi, Done, Bogdan, Arenas-Hernandez, Marcia, Miller, Derek, Gutierrez-Contreras, Pedro, Farias-Jofre, Marcelo, Aras, Siddhesh, Grossman, Lawrence I., Tarca, Adi L., Gomez-Lopez, Nardhy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462488/ https://www.ncbi.nlm.nih.gov/pubmed/35993366 http://dx.doi.org/10.1172/jci.insight.158238 |
Ejemplares similares
-
Exhausted and Senescent T Cells at the Maternal-Fetal Interface in Preterm and Term Labor
por: Slutsky, Rebecca, et al.
Publicado: (2019) -
Clarithromycin prevents preterm birth and neonatal mortality by dampening alarmin-induced maternal–fetal inflammation in mice
por: Galaz, Jose, et al.
Publicado: (2022) -
Regulatory T Cells Play a Role in a Subset of Idiopathic Preterm Labor/Birth and Adverse Neonatal Outcomes
por: Gomez-Lopez, Nardhy, et al.
Publicado: (2020) -
Host-microbiome interactions in distinct subsets of preterm labor and birth
por: Galaz, Jose, et al.
Publicado: (2023) -
A single-cell atlas of murine reproductive tissues during preterm labor
por: Garcia-Flores, Valeria, et al.
Publicado: (2023)