UCP2 modulates cardiomyocyte cell cycle activity, acetyl-CoA, and histone acetylation in response to moderate hypoxia

Developmental cardiac tissue is regenerative while operating under low oxygen. After birth, ambient oxygen is associated with cardiomyocyte cell cycle exit and regeneration. Likewise, cardiac metabolism undergoes a shift with cardiac maturation. Whether there are common regulators of cardiomyocyte c...

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Detalles Bibliográficos
Autores principales: Rigaud, Vagner O.C., Zarka, Clare, Kurian, Justin, Harlamova, Daria, Elia, Andrea, Kasatkin, Nicole, Johnson, Jaslyn, Behanan, Michael, Kraus, Lindsay, Pepper, Hannah, Snyder, Nathaniel W., Mohsin, Sadia, Houser, Steven R., Khan, Mohsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462500/
https://www.ncbi.nlm.nih.gov/pubmed/35771638
http://dx.doi.org/10.1172/jci.insight.155475

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