Cargando…

The UIP/IPF fibroblastic focus is a collagen biosynthesis factory embedded in a distinct extracellular matrix

Usual interstitial pneumonia (UIP) is a histological pattern characteristic of idiopathic pulmonary fibrosis (IPF). The UIP pattern is patchy with histologically normal lung adjacent to dense fibrotic tissue. At this interface, fibroblastic foci (FF) are present and are sites where myofibroblasts an...

Descripción completa

Detalles Bibliográficos
Autores principales: Herrera, Jeremy A., Dingle, Lewis, Montero, M. Angeles, Venkateswaran, Rajamiyer V., Blaikley, John F., Lawless, Craig, Schwartz, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462507/
https://www.ncbi.nlm.nih.gov/pubmed/35852874
http://dx.doi.org/10.1172/jci.insight.156115