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Peroxisomal very long-chain fatty acid transport is targeted by herpesviruses and the antiviral host response

Very long-chain fatty acids (VLCFA) are critical for human cytomegalovirus replication and accumulate upon infection. Here, we used Epstein-Barr virus (EBV) infection of human B cells to elucidate how herpesviruses target VLCFA metabolism. Gene expression profiling revealed that, despite a general i...

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Detalles Bibliográficos
Autores principales: Weinhofer, Isabelle, Buda, Agnieszka, Kunze, Markus, Palfi, Zsofia, Traunfellner, Matthäus, Hesse, Sarah, Villoria-Gonzalez, Andrea, Hofmann, Jörg, Hametner, Simon, Regelsberger, Günther, Moser, Ann B., Eichler, Florian, Kemp, Stephan, Bauer, Jan, Kühl, Jörn-Sven, Forss-Petter, Sonja, Berger, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462615/
https://www.ncbi.nlm.nih.gov/pubmed/36085307
http://dx.doi.org/10.1038/s42003-022-03867-y